[HTML][HTML] Protein-protein interaction networks (PPI) and complex diseases

N Safari-Alighiarloo, M Taghizadeh… - … and Hepatology from …, 2014 - ncbi.nlm.nih.gov
The physical interaction of proteins which lead to compiling them into large densely
connected networks is a noticeable subject to investigation. Protein interaction networks are …

Graph-based methods for analysing networks in cell biology

T Aittokallio, B Schwikowski - Briefings in bioinformatics, 2006 - academic.oup.com
Availability of large-scale experimental data for cell biology is enabling computational
methods to systematically model the behaviour of cellular networks. This review surveys the …

Chapter 4: Protein interactions and disease

MW Gonzalez, MG Kann - PLoS computational biology, 2012 - journals.plos.org
Proteins do not function in isolation; it is their interactions with one another and also with
other molecules (eg DNA, RNA) that mediate metabolic and signaling pathways, cellular …

Network pharmacology, molecular docking integrated surface plasmon resonance technology reveals the mechanism of Toujie Quwen Granules against coronavirus …

M Ye, G Luo, D Ye, M She, N Sun, YJ Lu, J Zheng - Phytomedicine, 2021 - Elsevier
Abstract Background The Coronavirus disease 2019 pneumonia broke out in 2019 (COVID-
19) and spread rapidly, which causes serious harm to the health of people and a huge …

Network properties revealed through matrix functions

E Estrada, DJ Higham - SIAM review, 2010 - SIAM
The emerging field of network science deals with the tasks of modeling, comparing, and
summarizing large data sets that describe complex interactions. Because pairwise affinity …

Affinity purification–mass spectrometry and network analysis to understand protein-protein interactions

JH Morris, GM Knudsen, E Verschueren, JR Johnson… - Nature protocols, 2014 - nature.com
By determining protein-protein interactions in normal, diseased and infected cells, we can
improve our understanding of cellular systems and their reaction to various perturbations. In …

MTGO: PPI network analysis via topological and functional module identification

D Vella, S Marini, F Vitali, D Di Silvestre, G Mauri… - Scientific reports, 2018 - nature.com
Protein-protein interaction (PPI) networks are viable tools to understand cell functions,
disease machinery, and drug design/repositioning. Interpreting a PPI, however, it is a …

[PDF][PDF] Complejidad y transdisciplinariedad en el campo de la salud colectiva: evaluación de conceptos y aplicaciones

N Almeida-Filho - Salud colectiva, 2006 - SciELO Public Health
Varios elementos epistemológicos y metodológicos han sido propuestos como tendencia
alternativa a la ciencia contemporánea, agrupados bajo el rótulo de" nuevo paradigma" y …

Protein interactions and disease: computational approaches to uncover the etiology of diseases

MG Kann - Briefings in bioinformatics, 2007 - academic.oup.com
The genomic era has been characterised by vast amounts of data from diverse sources,
creating a need for new tools to extract biologically meaningful information. Bioinformatics is …

Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese maternities

H Zhu, H Xiao, L Li, M Yang, Y Lin, J Zhou, X Zhang… - Cell Genomics, 2024 - cell.com
Glycemic traits are critical indicators of maternal and fetal health during pregnancy. We
performed genetic analysis for five glycemic traits in 14,744 Chinese pregnant women. Our …