Peptide-based fibrin-targeting probes for thrombus imaging

BL Oliveira, P Caravan - Dalton Transactions, 2017 - pubs.rsc.org
The development of new methods to image the onset and progression of thrombosis is an
unmet need. Non-invasive molecular imaging techniques targeting specific key structures …

Multicolor spectral photon-counting computed tomography: in vivo dual contrast imaging with a high count rate scanner

DP Cormode, S Si-Mohamed, D Bar-Ness… - Scientific reports, 2017 - nature.com
A new prototype spectral photon-counting computed tomography (SPCCT) based on a
modified clinical CT system has been developed. SPCCT analysis of the energy …

Evaluation of spectral photon counting computed tomography K-edge imaging for determination of gold nanoparticle biodistribution in vivo

S Si-Mohamed, DP Cormode, D Bar-Ness, M Sigovan… - Nanoscale, 2017 - pubs.rsc.org
Spectral photon counting computed tomography (SPCCT) is an emerging medical imaging
technology. SPCCT scanners record the energy of incident photons, which allows specific …

Nanotechnology combining photoacoustic kinetics and chemical kinetics for thrombosis diagnosis and treatment

H Tian, L Lin, Z Ba, F Xue, Y Li, W Zeng - Chinese Chemical Letters, 2021 - Elsevier
Thrombotic disease is a major problem that endangers human health. At present, MRI and
CT are commonly used clinically to diagnose thrombosis, and thrombolytic drugs are used …

Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography

PC Naha, KC Lau, JC Hsu, M Hajfathalian, S Mian… - Nanoscale, 2016 - pubs.rsc.org
Earlier detection of breast cancer reduces mortality from this disease. As a result, the
development of better screening techniques is a topic of intense interest. Contrast-enhanced …

A Fibrin Site‐Specific Nanoprobe for Imaging Fibrin‐Rich Thrombi and Preventing Thrombus Formation in Venous Vessels

Y Zhong, M Ye, L Huang, L Hu, F Li, Q Ni… - Advanced …, 2022 - Wiley Online Library
Venous thromboembolism (VTE) is a prevalent public health issue worldwide. Before
treatment, spatiotemporally accurate thrombus detection is essential. However, with the …

18F-GP1, a novel PET tracer designed for high-sensitivity, low-background detection of thrombi

J Lohrke, H Siebeneicher, M Berger… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Thromboembolic diseases such as myocardial infarction, stroke, transient ischemic attacks,
and pulmonary embolism are major causes of morbidity and mortality worldwide …

Multisite thrombus imaging and fibrin content estimation with a single whole-body PET scan in rats

F Blasi, BL Oliveira, TA Rietz, NJ Rotile… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Thrombosis is a leading cause of morbidity and mortality worldwide. Current
diagnostic strategies rely on imaging modalities that are specific for distinct vascular …

Detection and characterization of thrombosis in humans using fibrin-targeted positron emission tomography and magnetic resonance

D Izquierdo-Garcia, P Désogère, AL Philip… - Cardiovascular …, 2022 - jacc.org
Objectives The authors present a novel technique to detect and characterize LAA thrombus
in humans using combined positron emission tomography (PET)/cardiac magnetic …

Development of silica-encapsulated silver nanoparticles as contrast agents intended for dual-energy mammography

R Karunamuni, PC Naha, KC Lau, A Al-Zaki… - European …, 2016 - Springer
Objective Dual-energy (DE) mammography has recently entered the clinic. Previous
theoretical and phantom studies demonstrated that silver provides greater contrast than …