Future therapies targeted towards eliminating Candida biofilms and associated infections

H Bandara, VH Matsubara… - Expert review of anti …, 2017 - Taylor & Francis
Introduction: Candida species are common human commensals and cause either superficial
or invasive opportunistic infections. The biofilm form of candida as opposed to its …

Formulation Strategies for Enhancing Pharmaceutical and Nutraceutical Potential of Sesamol: A Natural Phenolic Bioactive

AB Nair, P Dalal, V Kadian, S Kumar, M Garg, R Rao… - Plants, 2023 - mdpi.com
Natural plants and their products continue to be the major source of phytoconstituents in
food and therapeutics. Scientific studies have evidenced the benefits of sesame oil and its …

Fungicidal action of geraniol against Candida albicans is potentiated by abrogated CaCdr1p drug efflux and fluconazole synergism

S Singh, Z Fatima, K Ahmad, S Hameed - PloS one, 2018 - journals.plos.org
Among the several mechanisms of multidrug resistance (MDR), overexpression of drug
efflux pumps CaCdr1p and CaMdr1p belonging to ATP binding cassette (ABC) and major …

Anticandidal Effect and Mechanisms of Monoterpenoid, Perillyl Alcohol against Candida albicans

MA Ansari, Z Fatima, S Hameed - PloS one, 2016 - journals.plos.org
This study explored the antifungal potential of perillyl alcohol (PA), a natural monoterpene
alcohol, against most prevalent human fungal pathogen C. albicans, its clinical isolates and …

Sesamol Induces Apoptosis-Like Cell Death in Leishmania donovani

R Ali, S Tabrez, SK Akand, F Rahman… - Frontiers in cellular …, 2021 - frontiersin.org
Background Visceral leishmaniasis (VL), caused by the protozoan parasite Leishmania
donovani (L. donovani), is the most severe form of leishmaniasis. It is largely responsible for …

In situ immobilized sesamol-quinone/carbon nanoblack-based electrochemical redox platform for efficient bioelectrocatalytic and immunosensor applications

M Gandhi, D Rajagopal, S Parthasarathy, S Raja… - ACS …, 2018 - ACS Publications
Most of the common redox mediators such as organic dyes and cyanide ligand-associated
metal complex systems that have been used for various electrochemical applications are …

[HTML][HTML] Effects of free fatty acids and peroxide on thermal loss of sesamol and formation of its transformation products in soybean oil

J Chen, Y Wang, W Liu, F Zhang, J Li, H Yang, Y Bi - LWT, 2022 - Elsevier
Sesamol, as a natural antioxidant used in edible oils, will be lost during heating process in
the pathway of volatilization or transformation. The present study was to (i) examine the …

Magnesium deprivation affects cellular circuitry involved in drug resistance and virulence in Candida albicans

S Hans, Z Fatima, S Hameed - Journal of Global Antimicrobial Resistance, 2019 - Elsevier
Objectives Candida albicans has to struggle for the limited micronutrients present in the
hostile host niche, including magnesium (Mg). The aim of this study was to examine the …

The sunflower jacalin Helja: biological and structural insights of its antifungal activity against Candida albicans

MV Del Río, MB Radicioni, AM Cutine, KV Mariño… - …, 2024 - academic.oup.com
The limited availability of efficient treatments for Candida infections and the increased
emergence of antifungal-resistant strains stimulates the search for new antifungal agents …

Octyl gallate triggers dysfunctional mitochondria leading to ROS driven membrane damage and metabolic inflexibility along with attenuated virulence in Candida …

V Saibabu, Z Fatima, K Ahmad, LA Khan… - Medical …, 2020 - academic.oup.com
Recently the high incidence of worldwide Candida infections has substantially increased.
The growing problem about toxicity of antifungal drugs and multidrug resistance aggravates …