Creating vascularised cellular environments in vitro is a current challenge in tissue
engineering and a bottleneck towards developing functional stem cell-derived microtissues …

Microfabricated organ-on-a-chips are rapidly becoming the gold standard for the testing of
safety and efficacy of therapeutics. A broad range of designs has emerged, but recreating …

Skeletal muscle-derived cells (SMDC) hold tremendous potential for replenishing
dysfunctional muscle lost due to disease or trauma. Current therapeutic usage of SMDC …

Cell polarity involves the asymmetric distribution of cellular components such as signaling
molecules and organelles within a cell, asymmetries of a cell” s shape as well as contacts …

Therapeutic monoclonal antibodies (mAbs) are an emerging and very active frontier in
clinical oncology, with hundred molecules currently in use or being tested. These treatments …

Major organs and tissues require close association with the vasculature during development
and for later function. Blood vessels are essential for efficient gas exchange and for …

Abstract Vascular Endothelial Cells (EC) plasticity is key to homeostasis and its disruption is
a hallmark of diseases such as cancer, atherosclerosis, and diabetes. The EC lineage has …

The cell morphology analysis is applicable to pathophysiology studies in biological samples.
In this work, digital images of Human Umbilical Vascular Endothelial Cells (HUVEC) were …