Antimicrobials against bacterial, viral and parasitic pathogens have transformed human and
animal health. Nevertheless, their widespread use (and misuse) has led to the emergence of …

Purpose Silver nanoparticles have been extensively used in pharmaceutical sciences as
therapeutic agents, including in drug delivery but their toxicity towards healthy tissue is not …

The COVID-19 pandemic has caused adverse health (severe respiratory, enteric and
systemic infections) and environmental impacts that have threatened public health and the …

Background SARS-CoV-2 variants continue to spread throughout the world and cause
waves of COVID-19 infections. It is important to find effective antiviral drugs to combat SARS …

De novo mutations in the synaptic GTPase activating protein (SynGAP) are associated with
neurological disorders like intellectual disability, epilepsy, and autism. SynGAP is also …

AIDS (Acquired immunodeficiency syndrome) is one of the chronic and potentially life-
threatening epidemics across the world. Hitherto, the non-existence of definitive drugs that …

Tropical Calcific Pancreatitis (TCP) is a chronic non-alcoholic pancreatitis characterised by
extensive calcification. The disease usually appears at a younger age and is more common …

Although multiple vaccines have been developed against infectious diseases, the rapid
emergence of new pathogens develops an urgent need for novel strategies to combat …

Stabilizing human telomere DNA G-quadruplex (G4) proves a promising anti-cancer
strategy. Though plenty of G4 stabilizing molecules have been reported, little is known about …

The ideal vaccines for combating diseases that may emerge in the future require more than
simply inactivating a few pathogenic strains. This study aims to provide a peptide-based …