Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

Autism spectrum disorders (ASD) and epilepsy are common neurological diseases of
childhood, with an estimated incidence of approximately 0.5–1% of the worldwide …

Heparan sulfate proteoglycans (HSPGs) are components of the cell surface and
extracellular matrix, which bear long polysaccharides called heparan sulfate (HS) attached …

The morphological alterations of cortical lamination observed in mouse models of
developmental hypothyroidism prompted the recognition that these experimental changes …

Autism spectrum disorders (ASDs) represent a spectrum of neurodevelopmental disorders
characterized by impaired social interaction, repetitive or restrictive behaviors, and problems …

Evidence for putative pathophysiological mechanisms of autism spectrum disorder (ASD),
including peripheral inflammation, blood–brain barrier disruption, white matter alterations …

Highlights•Dysregulation of embryonic and adult neurogenesis may be linked to
neuropsychiatric disorders.•Mutations in functionally distinct NPD-genes affect neural stem …

Autism spectrum disorder is a debilitating condition with possible neurodevelopmental
origins but unknown neuroanatomical correlates. Whereas investigators have paid much …

An early inflammatory insult is the most recognized risk factor associated with
neurodevelopmental psychiatric disorders, even more so than genetic variants. Notably …