With numerous recent advances, the field of therapeutic nucleic acid nanotechnology is now
poised for clinical translation supported by several examples of FDA-approved nucleic acid …

An orthogonal, noncovalent approach to direct the assembly of higher-order DNA origami
nanostructures is described. By incorporating perfluorinated tags into the edges of DNA …

Significant progress in DNA nanotechnology has accelerated the development of molecular
machines with functions like macroscale machines. However, the mobility of DNA self …

DNA nanostructures have considerable biomedical potential as intracellular delivery
vehicles as they are highly homogeneous and can be functionalized with high spatial …

Although rolling circle amplification (RCA) is an efficient method to produce DNA materials
for biomedical applications, it does not yield nano-sized products suitable for intracellular …

The unique structure‐directing properties of DNA origami nanostructures (DONs) show great
potential to specifically manipulate intracellular processes. We report an innovative concept …

Self-assembled nucleic acids perform biological, chemical, and mechanical work at the
nanoscale. DNA-based molecular machines have been designed here to perform work by …

A generic methodology for cytosolic delivery of large supramolecular multiprotein complexes
into living cells is described that takes advantage of the highly-controllable bottom-up …

The macro-scale behavior of engineering and biological materials is governed by the
composition of the constituent molecules. Therefore, understanding connections between …

DNA origami is a programmable self-assembly technique that combines a long single-
stranded DNA template strand with hundreds of shorter custom DNA strands (called" …