[HTML][HTML] Deciphering the performance of macrophages in tumour microenvironment: a call for precision immunotherapy
B Toledo, L Zhu Chen, M Paniagua-Sancho… - Journal of Hematology & …, 2024 - Springer
Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours
are known as tumour-associated macrophages (TAMs). These specialized immune cells …
are known as tumour-associated macrophages (TAMs). These specialized immune cells …
[HTML][HTML] The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and …
M Bakhtiyari, M Liaghat, F Aziziyan… - Cell Communication and …, 2023 - Springer
Acute myeloid leukemia (AML) comprises a multifarious and heterogeneous array of
illnesses characterized by the anomalous proliferation of myeloid cells in the bone marrow …
illnesses characterized by the anomalous proliferation of myeloid cells in the bone marrow …
[HTML][HTML] Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC
X Wu, W Lu, W Zhang, D Zhang, H Mei, M Zhang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: The treatment of triple-negative breast cancer (TNBC) is one of the main
focuses and key difficulties because of its heterogeneity, and the source of this …
focuses and key difficulties because of its heterogeneity, and the source of this …
[HTML][HTML] Therapeutic liposomal combination to enhance chemotherapy response and immune activation of tumor microenvironment
Multiple oxaliplatin-resistance mechanisms have been proposed such as increase of anti-
inflammatory M2 macrophages and lack of cytotoxic T-cells. Thereby oxaliplatin …
inflammatory M2 macrophages and lack of cytotoxic T-cells. Thereby oxaliplatin …
Effectiveness of Rhenium (I)-diselenoether Low Doses in a Triple-negative Breast Cancer Chicken Embryo Model
P Collery, C Prunier, E Dosda, J Viallet… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Rhenium (I)-diselenoether (Re-diSe) is a promising anticancer agent
composed of one rhenium and two selenium atoms. Its effectiveness was established in …
composed of one rhenium and two selenium atoms. Its effectiveness was established in …
Nanomedicine as a multimodal therapeutic paradigm against cancer: on the way forward in advancing precision therapy
P Sandbhor, P Palkar, S Bhat, G John, JS Goda - Nanoscale, 2024 - pubs.rsc.org
Recent years have witnessed dramatic improvements in nanotechnology-based cancer
therapeutics, and it continues to evolve from the use of conventional therapies …
therapeutics, and it continues to evolve from the use of conventional therapies …
[HTML][HTML] Prolactin Drives Iron Release from Macrophages and Uptake in Mammary Cancer Cells through CD44
R Farrell, N Pascuzzi, YL Chen, M Kim… - International Journal of …, 2024 - mdpi.com
Iron is an essential element for human health. In humans, dysregulated iron homeostasis
can result in a variety of disorders and the development of cancers. Enhanced uptake …
can result in a variety of disorders and the development of cancers. Enhanced uptake …
[HTML][HTML] Deciphering the Immune Microenvironment at the Forefront of Tumor Aggressiveness by Constructing a Regulatory Network with Single-Cell and Spatial …
K Xu, D Yu, S Zhang, L Chen, Z Liu, L Xie - Genes, 2024 - mdpi.com
The heterogeneity and intricate cellular architecture of complex cellular ecosystems play a
crucial role in the progression and therapeutic response of cancer. Understanding the …
crucial role in the progression and therapeutic response of cancer. Understanding the …
m6A‐and m5C‐modified lncRNAs orchestrate the prognosis in cutaneous melanoma and m6A‐modified LINC00893 regulates cutaneous melanoma cell metastasis
HZ Shi, CC Tian, MY Wu, L Ma… - Skin Research and …, 2024 - Wiley Online Library
Background As the most important modifications on the RNA level, N6‐methyladenosine
(m6A‐) and 5‐methylcytosine (m5C‐) modification could have a direct influence on the …
(m6A‐) and 5‐methylcytosine (m5C‐) modification could have a direct influence on the …
Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling
MF Oliveira, JP Romero, M Chung, S Williams… - bioRxiv, 2024 - biorxiv.org
Colorectal cancer (CRC) is the second-deadliest cancer in the world, yet a deeper
understanding of spatial patterns of gene expression in the tumor microenvironment (TME) …
understanding of spatial patterns of gene expression in the tumor microenvironment (TME) …