Long-term depression in the CNS

GL Collingridge, S Peineau, JG Howland… - Nature reviews …, 2010 - nature.com
Long-term depression (LTD) in the CNS has been the subject of intense investigation as a
process that may be involved in learning and memory and in various pathological …

Metabotropic glutamate receptors: physiology, pharmacology, and disease

CM Niswender, PJ Conn - Annual review of pharmacology and …, 2010 - annualreviews.org
The metabotropic glutamate receptors (mGluRs) are family C G-protein-coupled receptors
that participate in the modulation of synaptic transmission and neuronal excitability …

Metabotropic glutamate receptors: from the workbench to the bedside

F Nicoletti, J Bockaert, GL Collingridge, PJ Conn… - …, 2011 - Elsevier
Metabotropic glutamate (mGlu) receptors were discovered in the mid 1980s and originally
described as glutamate receptors coupled to polyphosphoinositide hydrolysis. Almost 6500 …

Glutamate receptor function in learning and memory

G Riedel, B Platt, J Micheau - Behavioural brain research, 2003 - Elsevier
The contribution of glutamate to synaptic transmission, plasticity and development is well
established; current evidence is based on diverse approaches to decipher function and …

[图书][B] What's wrong with my mouse?: behavioral phenotyping of transgenic and knockout mice

JN Crawley - 2007 - books.google.com
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

R Shigemoto, A Kinoshita, E Wada… - Journal of …, 1997 - Soc Neuroscience
Neurotransmission in the hippocampus is modulated variously through presynaptic
metabotropic glutamate receptors (mGluRs). To establish the precise localization of …

Glutamate receptors in the mammalian central nervous system

S Ozawa, H Kamiya, K Tsuzuki - Progress in neurobiology, 1998 - Elsevier
Glutamate receptors (GluRs) mediate most of the excitatory neurotransmission in the
mammalian central nervous system (CNS). In addition, they are involved in plastic changes …

Cellular and synaptic adaptations mediating opioid dependence

JT Williams, MDJ Christie… - Physiological …, 2001 - journals.physiology.org
Although opioids are highly effective for the treatment of pain, they are also known to be
intensely addictive. There has been a massive research investment in the development of …

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

JP Pin, T Galvez, L Prézeau - Pharmacology & therapeutics, 2003 - Elsevier
G-protein-coupled receptors (GPCRs) represent one of the largest gene families in the
animal genome. These receptors can be classified into several groups based on the …

Synaptic plasticity at hippocampal mossy fibre synapses

RA Nicoll, D Schmitz - Nature Reviews Neuroscience, 2005 - nature.com
The dentate gyrus provides the main input to the hippocampus. Information reaches the CA3
region through mossy fibre synapses made by dentate granule cell axons. Synaptic plasticity …