Epidemiology and prevention of renal cell carcinoma

T Makino, S Kadomoto, K Izumi, A Mizokami - Cancers, 2022 - mdpi.com
Simple Summary The incidence of renal cell carcinoma (RCC) rises globally with the highest
rates in developed countries. This indicates not only the impact of advanced imaging, but …

Epigenetic biomarkers of renal cell carcinoma for liquid biopsy tests

R Kubiliute, S Jarmalaite - International journal of molecular sciences, 2021 - mdpi.com
Renal cell carcinomas (RCC) account for 2–3% of the global cancer burden and are
characterized by the highest mortality rate among all genitourinary cancers. However …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Associations between arsenic exposure and global posttranslational histone modifications among adults in Bangladesh

Y Chervona, MN Hall, A Arita, F Wu, H Sun… - … , biomarkers & prevention, 2012 - AACR
Abstract Background: Exposure to arsenic (As) is associated with an increased risk of
several cancers as well as cardiovascular disease, and childhood neuro-developmental …

Recent advances in the management of clear cell renal cell carcinoma: novel biomarkers and targeted therapies

V Schiavoni, R Campagna, V Pozzi, M Cecati… - Cancers, 2023 - mdpi.com
Simple Summary The aim of the present review is to discuss novel prognostic and
therapeutic markers for clear cell renal cell carcinoma, a subtype of renal cell carcinoma …

Epigenetic biomarkers in urological tumors: A systematic review

C Jeronimo, R Henrique - Cancer letters, 2014 - Elsevier
Prostate, bladder, kidney and testis cancers, the most common genitourinary (GU)
neoplasms, are generally clinically silent at their earliest stages when curative treatment is …

Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma

J Ellinger, P Kahl, C Mertens… - … journal of cancer, 2010 - Wiley Online Library
Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested
that global histone modifications are predictors of cancer recurrence in various tumor …

The role of epigenetics in the progression of clear cell renal cell carcinoma and the basis for future epigenetic treatments

JC Angulo, C Manini, JI López, A Pueyo, B Colás… - Cancers, 2021 - mdpi.com
Simple Summary The accumulated evidence on the role of epigenetic markers of prognosis
in clear cell renal cell carcinoma (ccRCC) is reviewed, as well as state of the art on …

Global histone acetylation levels: prognostic relevance in patients with renal cell carcinoma

D Mosashvilli, P Kahl, C Mertens, S Holzapfel… - Cancer …, 2010 - Wiley Online Library
Epigenetic alterations play an important role in carcinogenesis. Recent studies have
suggested that global histone modifications are predictors of cancer recurrence in various …

Epigenome aberrations: emerging driving factors of the clear cell renal cell carcinoma

A Mehdi, Y Riazalhosseini - International journal of molecular sciences, 2017 - mdpi.com
Clear cell renal cell carcinoma (ccRCC), the most common form of Kidney cancer, is
characterized by frequent mutations of the von Hippel-Lindau (VHL) tumor suppressor gene …