The biological and clinical consequences of RNA splicing factor U2AF1 mutation in myeloid malignancies
Y Zhao, W Cai, Y Hua, X Yang, J Zhou - Cancers, 2022 - mdpi.com
Simple Summary U2 small nuclear RNA auxiliary factor 1 (U2AF1) is one of the most
important RNA splicing genes involved in regulating the alternative splicing of pre-mRNA …
important RNA splicing genes involved in regulating the alternative splicing of pre-mRNA …
Aberrant alternative splicing in U2af1/Tet2 double mutant mice contributes to major hematological phenotypes
C Martínez-Valiente, C Garcia-Ruiz, B Rosón… - International journal of …, 2021 - mdpi.com
Mutations in splicing factors are recurrent somatic alterations identified in myelodysplastic
syndromes (MDS) and they frequently coincide with mutations in epigenetic factors. About …
syndromes (MDS) and they frequently coincide with mutations in epigenetic factors. About …
Multi-omics profiling of U2AF1 mutants dissects pathogenic mechanisms affecting RNA granules in myeloid malignancies
Somatic mutations in splicing factors are of significant interest in myeloid malignancies and
other cancers. U2AF1, together with U2AF2, is essential for 3'splice site recognition. U2AF1 …
other cancers. U2AF1, together with U2AF2, is essential for 3'splice site recognition. U2AF1 …
Desarrollo y caracterización de un modelo de ratón doble mutante en U2af1 y Tet2 para el estudio de los Síndromes Mielodisplásicos.
C Martínez Valiente - 2022 - riunet.upv.es
[ES] Los síndromes mielodisplásicos (SMD) constituyen un grupo heterogéneo de
enfermedades de naturaleza clonal caracterizadas por presentar una hematopoyesis …
enfermedades de naturaleza clonal caracterizadas por presentar una hematopoyesis …