Role of hemodynamics in initiation/growth of intracranial aneurysms

MR Diagbouga, S Morel, P Bijlenga… - European journal of …, 2018 - Wiley Online Library
Background Intracranial aneurysm (IA) is a disease of the vascular wall resulting in
abnormal enlargement of the vessel lumen. It is a common pathology with a prevalence of …

In vivo cerebral aneurysm models

JW Thompson, O Elwardany, DJ McCarthy… - Neurosurgical …, 2019 - thejns.org
Cerebral aneurysm rupture is a devastating event resulting in subarachnoid hemorrhage
and is associated with significant morbidity and death. Up to 50% of individuals do not …

A new endoluminal, flow-disrupting device for treatment of saccular aneurysms

DF Kallmes, YH Ding, D Dai, R Kadirvel, DA Lewis… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—We report a preclinical study of a new endoluminal device for
aneurysm occlusion to test the hypothesis that the device, even without use of intrasaccular …

Cellular mechanisms of aneurysm occlusion after treatment with a flow diverter

R Kadirvel, YH Ding, D Dai, I Rezek, DA Lewis… - Radiology, 2014 - pubs.rsna.org
Purpose To characterize the progression of healing across aneurysm necks following
treatment with a flow diverter in a rabbit aneurysm model. Materials and Methods With …

A second-generation, endoluminal, flow-disrupting device for treatment of saccular aneurysms

DF Kallmes, YH Ding, D Dai… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: We report a preclinical study of a second-generation
endoluminal device (Pipeline Embolization Device [PED-2] for aneurysmal occlusion and …

The Woven EndoBridge: a new aneurysm occlusion device

YH Ding, DA Lewis, R Kadirvel… - American journal of …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The WEB device is an intrasaccular ellipsoid braided-wire
embolization device designed to provide flow disruption along the aneurysm neck. The …

New expandable hydrogel-platinum coil hybrid device for aneurysm embolization

DF Kallmes, NH Fujiwara - American Journal of …, 2002 - Am Soc Neuroradiology
This study introduces a new, hybrid embolic device that in addition to offering all the
important attributes of existing detachable platinum coils also shows an enhanced ability to …

Wall apposition is a key factor for aneurysm occlusion after flow diversion: a histologic evaluation in 41 rabbits

A Rouchaud, C Ramana, W Brinjikji… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Robust wall apposition for flow-diverter stents may be
important for endothelialization. Using a large series of experimental aneurysms treated with …

Angiographic and histologic analysis of experimental aneurysms embolized with platinum coils, Matrix, and HydroCoil

YH Ding, D Dai, DA Lewis, HJ Cloft… - American Journal of …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A report directly comparing platinum coils, Matrix coils,
and Hydro Coil s in a single animal model does not currently exist. We evaluated and …

Hemodynamics of cerebral aneurysms: computational analyses of aneurysm progress and treatment

W Jeong, K Rhee - Computational and mathematical methods …, 2012 - Wiley Online Library
The progression of a cerebral aneurysm involves degenerative arterial wall remodeling.
Various hemodynamic parameters are suspected to be major mechanical factors related to …