Propolis extract and its bioactive compounds—From traditional to modern extraction technologies

J Šuran, I Cepanec, T Mašek, B Radić, S Radić… - Molecules, 2021 - mdpi.com
Propolis is a honeybee product known for its antioxidant, anti-inflammatory, anticancer, and
antimicrobial effects. It is rich in bioactive molecules whose content varies depending on the …

Evidence on the health benefits of supplemental propolis

A Braakhuis - Nutrients, 2019 - mdpi.com
Propolis is a honey-related product with reported health benefits such as improved
immunity, lowered blood pressure, treated allergies and skin conditions. A literature review …

Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

A Rasul, FM Millimouno, W Ali Eltayb… - BioMed research …, 2013 - Wiley Online Library
Pinocembrin (5, 7‐dihydroxyflavanone) is one of the primary flavonoids isolated from the
variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and …

Reactive oxygen species and ischemic cerebrovascular disease

I Olmez, H Ozyurt - Neurochemistry international, 2012 - Elsevier
Stroke is an emerging major health problem often resulting in death or disability.
Hyperlipidemia, high blood pressure and diabetes are well established risk factors …

The Nrf2/HO‐1 Axis as targets for flavanones: Neuroprotection by pinocembrin, naringenin, and Eriodictyol

S Habtemariam - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Flavanones are a group of flavonoids that derive from their immediate chalcone precursors
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …

Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia

X Lan, X Han, Q Li, Q Li, Y Gao, T Cheng, J Wan… - Brain, behavior, and …, 2017 - Elsevier
Neuroinflammation is a major contributor to intracerebral hemorrhage (ICH) progression, but
no drug is currently available to reduce this response and protect against ICH-induced …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy

J Wu, G Du, J Zhou, J Chen - Metabolic engineering, 2013 - Elsevier
Flavonoids are valuable natural products widely used in human health and nutrition. Recent
advances in synthetic biology and metabolic engineering have yielded improved strain titers …

Polyphenols mediate neuroprotection in cerebral ischemic stroke—an update

SA Abdelsalam, K Renu, HA Zahra, BM Abdallah… - Nutrients, 2023 - mdpi.com
Stroke is one of the main causes of mortality and disability, and it is due to be included in
monetary implications on wellbeing frameworks around the world. Ischemic stroke is caused …

Antioxidant properties of honey and its role in preventing health disorder

MI Khalil, SA Sulaiman, L Boukraa - The open nutraceuticals …, 2010 - benthamopen.com
Honey is being used since long time both in medical and domestic needs, but only recently
its antioxidant property has come to limelight. With increasing demand for antioxidant supply …