Medicines regulation in Africa: current state and opportunities

M Ndomondo-Sigonda, J Miot, S Naidoo… - Pharmaceutical …, 2017 - Springer
Sound regulatory systems are critical for protecting public health against use of medical
products which do not meet international standards of quality, safety and efficacy. This …

Neisseria meningitidis: using genomics to understand diversity, evolution and pathogenesis

DA Caugant, OB Brynildsrud - Nature Reviews Microbiology, 2020 - nature.com
Meningococcal disease remains an important cause of morbidity and death worldwide
despite the development and increasing implementation of effective vaccines. Elimination of …

Impact of introduction of rapid diagnostic tests for malaria on antibiotic prescribing: analysis of observational and randomised studies in public and private healthcare …

H Hopkins, KJ Bruxvoort, ME Cairns, CIR Chandler… - bmj, 2017 - bmj.com
Objectives To examine the impact of use of rapid diagnostic tests for malaria on prescribing
of antimicrobials, specifically antibiotics, for acute febrile illness in Africa and Asia. Design …

Meningococcal serogroups and surveillance: a systematic review and survey

ME Peterson, Y Li, A Bita, A Moureau… - Journal of global …, 2018 - pmc.ncbi.nlm.nih.gov
Background Meningococcal disease continues to be a global public health concern due to
its epidemic potential, severity, and sequelae. The global epidemiological data on …

[HTML][HTML] Deciphering the burden of meningococcal disease: conventional and under-recognized elements

F Martinón-Torres - Journal of Adolescent Health, 2016 - Elsevier
Invasive meningococcal disease remains a substantial global public health burden despite
being vaccine-preventable worldwide. More than one million cases are reported annually …

Multicomponent meningococcal serogroup B vaccination elicits cross-reactive immunity in infants against genetically diverse serogroup C, W and Y invasive disease …

A Biolchi, G De Angelis, M Moschioni, S Tomei… - Vaccine, 2020 - Elsevier
Background The multicomponent meningococcal serogroup B vaccine (4CMenB) is
currently indicated for active immunization against invasive meningococcal disease caused …

Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa

OB Brynildsrud, V Eldholm, J Bohlin… - Proceedings of the …, 2018 - National Acad Sciences
In the African meningitis belt, a region of sub-Saharan Africa comprising 22 countries from
Senegal in the west to Ethiopia in the east, large epidemics of serogroup A meningococcal …

An Overview of Neisseria meningitidis

S Hollingshead, CM Tang - Neisseria meningitidis: Methods and Protocols, 2019 - Springer
Neisseria meningitidis (the meningococcus) is a member of the normal nasopharyngeal
microbiome in healthy individuals, but can cause septicemia and meningitis in susceptible …

'Learn from the lessons and don't forget them': identifying transferable lessons for COVID-19 from meningitis A, yellow fever and Ebola virus disease vaccination …

J Collins, R Westerveld, KA Nelson, H Rohan… - BMJ global …, 2021 - gh.bmj.com
Introduction COVID-19 vaccines are now being distributed to low-and middle-income
countries (LMICs), with global urgency surrounding national vaccination plans. LMICs have …

[HTML][HTML] Towards understanding the epidemiology of Neisseria meningitidis in the African meningitis belt: a multi-disciplinary overview

L Agier, N Martiny, O Thiongane, JE Mueller… - International Journal of …, 2017 - Elsevier
Objectives Neisseria meningitidis is the major cause of seasonal meningitis epidemics in the
African meningitis belt. In the changing context of a reduction in incidence of serogroup A …