Schistosomiasis is a major cause of morbidity in humans invoked by chronic infection with
parasitic trematodes of the genus Schistosoma. Schistosomes have a complex life-cycle …

During recent years, it has become clear that polymorphonuclear neutrophils are remarkably
versatile cells, whose functions go far beyond phagocytosis and killing. In fact, besides …

Neutrophils are the most abundant of the circulating immune cells and are the first to be
recruited to sites of inflammation. Neutrophils are a heterogeneous group of immune cells …

MicroRNAs (miRNAs) play a variety of roles in diverse biological processes at the post-
transcriptional regulatory level. Although numerous miRNAs have been identified in …

Schistosomiasis is the most important helminth disease in the world from a public health
perspective. S mansoni and S japonicum account for the majority of global intestinal …

Neutrophil extracellular traps (NETs) are DNA fibers associated with histones, enzymes from
neutrophil granules and anti-microbial peptides. NETs are released in a process …

Neutrophil extracellular traps (NETs) are networks of extracellular chromosomal DNA fibers,
histones, and cytoplasmic granule proteins. The release of NET components from …

Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

Schistosomiasis is a disease of global significance, with severity and pathology directly
related to how the host responds to infection. The immunological narrative of …

The deeply rooted, intricate relationship between the Schistosoma parasite and the human
host has enabled the parasite to successfully survive within the host and surreptitiously …