Connectivity and functionality of the globus pallidus externa under normal conditions and Parkinson's disease
The globus pallidus externa (GPe) functions as a central hub in the basal ganglia for
processing motor and non-motor information through the creation of complex connections …
processing motor and non-motor information through the creation of complex connections …
Cellular and synaptic dysfunctions in Parkinson's disease: stepping out of the striatum
N Mallet, L Delgado, M Chazalon, C Miguelez… - Cells, 2019 - mdpi.com
The basal ganglia (BG) are a collection of interconnected subcortical nuclei that participate
in a great variety of functions, ranging from motor programming and execution to procedural …
in a great variety of functions, ranging from motor programming and execution to procedural …
Canceling actions involves a race between basal ganglia pathways
Salient cues can prompt the rapid interruption of planned actions. It has been proposed that
fast, reactive behavioral inhibition involves specific basal ganglia pathways, and we tested …
fast, reactive behavioral inhibition involves specific basal ganglia pathways, and we tested …
Beyond reward prediction errors: the role of dopamine in movement kinematics
We recorded activity of dopamine (DA) neurons in the substantia nigra pars compacta in
unrestrained mice while monitoring their movements with video tracking. Our approach …
unrestrained mice while monitoring their movements with video tracking. Our approach …
Functional dissection of basal ganglia inhibitory inputs onto substantia nigra dopaminergic neurons
Substantia nigra (SNc) dopaminergic neurons respond to aversive stimuli with inhibitory
pauses in firing followed by transient rebound activation. We tested integration of inhibitory …
pauses in firing followed by transient rebound activation. We tested integration of inhibitory …
Dissociable roles of pallidal neuron subtypes in regulating motor patterns
We have previously established that PV+ neurons and Npas1+ neurons are distinct neuron
classes in the external globus pallidus (GPe): they have different topographical …
classes in the external globus pallidus (GPe): they have different topographical …
Striosomes control dopamine via dual pathways paralleling canonical basal ganglia circuits
Balanced activity of canonical direct D1 and indirect D2 basal ganglia pathways is
considered a core requirement for normal movement, and their imbalance is an etiologic …
considered a core requirement for normal movement, and their imbalance is an etiologic …
A non-canonical striatopallidal Go pathway that supports motor control
In the classical model of the basal ganglia, direct pathway striatal projection neurons
(dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to …
(dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to …
Intrinsic and integrative properties of substantia nigra pars reticulata neurons
FM Zhou, CR Lee - Neuroscience, 2011 - Elsevier
The GABA projection neurons of the substantia nigra pars reticulata (SNr) are output
neurons for the basal ganglia and thus critical for movement control. Their most striking …
neurons for the basal ganglia and thus critical for movement control. Their most striking …
Propagation of oscillations in the indirect pathway of the basal ganglia
Oscillatory signals propagate in the basal ganglia from prototypic neurons in the external
globus pallidus (GPe) to their target neurons in the substantia nigra pars reticulata (SNr) …
globus pallidus (GPe) to their target neurons in the substantia nigra pars reticulata (SNr) …