Understanding of molecular mechanisms of tumor growth has an increasing impact on the
development of diagnostics and targeted therapy of human neoplasia. In this review, we …

Purpose: Non–small cell lung cancer (NSCLC) is the most common cause of cancer-related
deaths worldwide. There is an unmet need to develop novel clinically relevant models of …

The individual and combined toxicities of amoxicillin, erythromycin, levofloxacin, norfloxacin
and tetracycline have been examined in two organisms representative of the aquatic …

This brief perspective article focuses on the most common errors and pitfalls, as well as the
do's and don'ts in drug combination studies, in terms of experimental design, data …

Patient-derived xenograft (PDX) models are powerful tools for understanding cancer biology
and drug discovery. In this study, a polymeric nano-sized drug delivery system poly …

Each year ecotoxicological problems become increasingly complex and encompass
broader spatial and temporal scales. Our practical understanding must evolve accordingly to …

This brief article focuses on two aims: i) To investigate the in vitro pharmaco-dynamic
interactions of combining synthetic potent microtubule targeting anticancer agent, Fludelone …

Abstract Background Circular RNAs are a class of endogenous RNAs with various functions
in eukaryotic cells. Worthy of note, circular RNAs play a critical role in cancer. Currently …

Cancer continues to be a prevalent and lethal disease, despite advances in tumor biology
research and chemotherapy development. Major obstacles in cancer treatment arise from …

The combined effects and toxicological interactions of perfluoroalkyl and polyfluoroalkyl
substances (PFAS) mixtures remain largely unknown even though they occur as complex …