A basic science view of acute kidney injury biomarkers

JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …

Cardiac surgery-associated acute kidney injury

H Mao, N Katz, W Ariyanon, L Blanca-Martos… - Blood purification, 2014 - karger.com
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious
postoperative complication of cardiac surgery requiring cardiopulmonary bypass (CPB), and …

Acute kidney injury after major surgery: a retrospective analysis of veterans health administration data

ME Grams, Y Sang, J Coresh, S Ballew… - American Journal of …, 2016 - Elsevier
Background Few trials of acute kidney injury (AKI) prevention after surgery have been
conducted, and most observational studies focus on AKI following cardiac surgery. The …

Update on cystatin C: incorporation into clinical practice

MG Shlipak, MD Mattes, CA Peralta - American Journal of Kidney Diseases, 2013 - Elsevier
Kidney function monitoring using creatinine-based glomerular filtration rate estimation is a
routine part of clinical practice. Emerging evidence has shown that cystatin C may improve …

Biomarkers in acute kidney injury

CL Edelstein - Biomarkers of Kidney Disease, 2017 - Elsevier
Blood urea nitrogen (BUN) and serum creatinine (SCr) are not very sensitive and specific
markers of kidney function in acute kidney injury (AKI) as they are influenced by many renal …

Plasma IL-6 and IL-10 concentrations predict AKI and long-term mortality in adults after cardiac surgery

WR Zhang, AX Garg, SG Coca… - Journal of the …, 2015 - journals.lww.com
Inflammation has an integral role in the pathophysiology of AKI. We investigated the
associations of two biomarkers of inflammation, plasma IL-6 and IL-10, with AKI and …

Patient selection and timing of continuous renal replacement therapy

M Ostermann, M Joannidis, A Pani, M Floris… - Blood purification, 2016 - karger.com
When and in whom to initiate continuous renal replacement therapy (CRRT) for acute kidney
injury (AKI) remains a highly controversial topic with large practice variation around the …

Chronic kidney disease following acute kidney injury—risk and outcomes

KCW Leung, M Tonelli, MT James - Nature Reviews Nephrology, 2013 - nature.com
In the past two decades, a substantial increase in the incidence of acute kidney injury (AKI)
and kidney injury requiring dialysis has occurred in North America. This increase has …

New biomarkers in acute kidney injury

A Rossiter, A La, JL Koyner, LG Forni - Critical Reviews in Clinical …, 2024 - Taylor & Francis
Acute kidney injury (AKI) is a commonly encountered clinical syndrome. Although it often
complicates community acquired illness, it is more common in hospitalized patients …

Phenotyping of acute kidney injury: beyond serum creatinine

DG Moledina, CR Parikh - Seminars in nephrology, 2018 - Elsevier
Acute kidney injury (AKI) is a common complication in hospitalized patients and is
associated with adverse short-and long-term outcomes. AKI is diagnosed by serum …