Background Epidemiological studies have frequently shown the concurrence of chronic pain
with symptoms of anxiety and depression, particularly in women. Animal models are useful …

The E3 ubiquitin ligase Ube3a is biallelically expressed in neural progenitors and glial cells,
suggesting that UBE3A gain-of-function mutations might cause neurodevelopmental …

The physiological similarities between mice and humans make them vital animal models in
biological and medical research. This paper explores the application of artificial intelligence …

Regression is a key feature of neurodevelopmental disorders such as autism spectrum
disorder, Fragile X syndrome, and Rett syndrome (RTT). RTT is caused by mutations in the X …

Neuropathic pain causes both sensory and emotional maladaptation. Preclinical animal
studies of neuropathic pain-induced negative affect could result in novel insights into the …

Neuropathic pain causes both sensory and emotional maladaptation. Preclinical animal
studies of neuropathic pain-induced negative affect could result in novel insights into the …

Background Epidemiological studies have frequently shown the concurrence of chronic pain
with symptoms of anxiety and depression, particularly in women. Animal models are useful …

This manuscript describes a battery of behavioral tests available to characterize Angelman
syndrome (AS)-like phenotypes in an established murine model of AS. We use the rotarod …

The investigation of aetiology and treatment of psychiatric symptoms and diseases remains
difficult. Animal models still provide a useful tool of investigation with high translational …

Mice are one of the frequently used animal models in science research whose behavioral
characteristics can provide much valuable information in biology, neuroscience, and …