The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Significance: Macrophages are crucial for tissue homeostasis. Based on their activation,
they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro …

Macrophages are versatile cells of the innate immune system that perform diverse functions
by responding to dynamic changes in their microenvironment. While the effects of soluble …

Macrophages perform critical functions for homeostasis and immune defense in tissues
throughout the body. These innate immune cells are capable of recognizing and clearing …

Recent years have witnessed significant progress in skeletal muscle tissue regeneration.
Numerous bioengineering approaches have been implemented to construct in vitro skeletal …

Fibrosis results from aberrant wound healing and is characterized by an accumulation of
extracellular matrix, impairing the function of an affected organ. Increased deposition of …

In situ tissue engineering using bioresorbable material implants-or scaffolds-that harness
the patient's immune response while guiding neotissue formation at the site of implantation …

Within the past 25 years, tissue engineering (TE) has grown enormously as a science and
as an industry. Although classically concerned with the recapitulation of tissue and organ …

Repair of injured skeletal muscle is a sophisticated process that uses immune, muscle,
perivascular, and neural cells. In acute injury, the robust endogenous repair process can …

In recent years, biomaterial-and scaffold-based immunomodulation strategies were
implemented in tissue regeneration efforts for manipulating macrophage polarization (aka …