Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Mass spectrometry-based metabolomics in health and medical science: A systematic review

X Zhang, Q Li, J Dou - RSC advances, 2020 - pubs.rsc.org
Metabolomics is the study of the investigation of small molecules derived from cellular and
organism metabolism, which reflects the outcomes of the complex network of biochemical …

An omics perspective on drug target discovery platforms

J Paananen, V Fortino - Briefings in bioinformatics, 2020 - academic.oup.com
The drug discovery process starts with identification of a disease-modifying target. This
critical step traditionally begins with manual investigation of scientific literature and …

Functional foods: exploring the health benefits of bioactive compounds from plant and animal sources

V Dixit, SW Joseph Kamal, P Bajrang Chole… - Journal of food …, 2023 - Wiley Online Library
“Let food be the medicine”(Hippocrates) is a historic quote that became the basis of food
science and nutraceuticals. Due to their possible therapeutic advantages, extracts from food …

Comprehensive metabolomic search for biomarkers to differentiate early stage hepatocellular carcinoma from cirrhosis

DJ Kim, EJ Cho, KS Yu, IJ Jang, JH Yoon, T Park… - Cancers, 2019 - mdpi.com
The established biomarker for hepatocellular carcinoma (HCC), serum α-fetoprotein (AFP),
has suboptimal performance in early disease stages. This study aimed to develop a …

Toxicometabolomics: small molecules to answer big toxicological questions

AM Araújo, F Carvalho, P Guedes de Pinho… - Metabolites, 2021 - mdpi.com
Given the high biological impact of classical and emerging toxicants, a sensitive and
comprehensive assessment of the hazards and risks of these substances to organisms is …

Metabolomics in autoimmune diseases: Focus on rheumatoid arthritis, systemic lupus erythematous, and multiple sclerosis

N Yoon, AK Jang, Y Seo, BH Jung - Metabolites, 2021 - mdpi.com
The metabolomics approach represents the last downstream phenotype and is widely used
in clinical studies and drug discovery. In this paper, we outline recent advances in the …

A metabolic pattern in healthy subjects given a single dose of metformin: a metabolomics approach

LA Dahabiyeh, M Mujammami, T Arafat… - Frontiers in …, 2021 - frontiersin.org
Metformin is a widely prescribed medication for the treatment of type 2 diabetes mellitus
(T2DM). It possesses effective roles in various disorders, including cancer, dyslipidemia, and …

[HTML][HTML] Present and future of metabolic and metabolomics studies focused on classical psychedelics in humans

F Madrid-Gambin, D Fabregat-Safont… - Biomedicine & …, 2023 - Elsevier
Psychedelics are classical hallucinogen drugs that induce a marked altered state of
consciousness. In recent years, there has been renewed attention to the possible use of …

Cannabis-responsive biomarkers: A pharmacometabolomics-based application to evaluate the impact of medical cannabis treatment on children with autism spectrum …

M Siani-Rose, S Cox, B Goldstein… - Cannabis and …, 2023 - liebertpub.com
Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions
that impact behavior, communication, social interaction, and learning abilities. Treatment of …