Pseudomonas aeruginosa epidemic high-risk clones and their association with horizontally-acquired β-lactamases: 2020 update

E del Barrio-Tofiño, C López-Causapé… - International journal of …, 2020 - Elsevier
Pseudomonas aeruginosa global clones associated with multidrug-resistant (MDR) and
extensively drug-resistant (XDR) phenotypes, denominated high-risk clones, are a growing …

OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Activity of imipenem/relebactam against Pseudomonas aeruginosa producing ESBLs and carbapenemases

S Mushtaq, D Meunier, A Vickers… - Journal of …, 2021 - academic.oup.com
Background ESBL-and carbapenemase-producing Pseudomonas aeruginosa are prevalent
in, for example, the Middle East, Eastern Europe and Latin America, though rarer elsewhere …

[HTML][HTML] Phenotypic and genotypic detection of carbapenemase production among gram negative bacteria isolated from hospital acquired infections

SK Vamsi, RS Moorthy, MN Hemiliamma… - Saudi Medical …, 2022 - ncbi.nlm.nih.gov
Objectives: To identify the carbapenemase producing Gram-negative bacteria (GNB) by
phenotypic methods and to confirm the presence of resistant genes using real-time …

[HTML][HTML] Domestically Acquired NDM-1–Producing Pseudomonas aeruginosa, Southern California, USA, 2023

HK Gray, OE Beaird, EA Smith… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
We describe a case of New Delhi metallo-β-lactamase 1–producing carbapenem-resistant
Pseudomonas aeruginosa (CRPA) in a transplant patient with multiple hospitalizations in …

Phenotypic and genomic comparison of the two most common ExoU-positive Pseudomonas aeruginosa clones, PA14 and ST235

S Fischer, S Dethlefsen, J Klockgether, B Tümmler - Msystems, 2020 - Am Soc Microbiol
Genotyping of 2,882 Pseudomonas aeruginosa isolates that had been collected during the
last 40 years identified the ExoU-positive lineages PA14 (ST253) and ST235 as the second …

[HTML][HTML] Characterization of Antimicrobial Resistance Mechanisms and Virulence Determinants in Colistin- and Carbapenem-Resistant Pseudomonas aeruginosa

E Kalaiarasan, A Alex, HB Narasimha, R Sehgal - Microbiology Research, 2024 - mdpi.com
Antibiotics like colistin can save patients infected with carbapenem-resistant Pseudomonas
aeruginosa. However, patients can succumb to such infections even if they undergo colistin …

High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update

VR Flores-Vega, S Partida-Sanchez, MA Ares… - Heliyon, 2025 - cell.com
Carbapenem-resistant Pseudomonas aeruginosa is defined by the World Health
Organization as a" high priority" in developing new antimicrobials. Indeed, the emergence …

Evaluation of efflux pumps overexpression and β-lactamase genes among colistin resistant Pseudomonas aeruginosa

M Abavisani, M Goudarzi, Z Ghalavand, B Hajikhani… - Gene Reports, 2021 - Elsevier
Pseudomonas aeruginosa (PA) is one of the major factors in severe opportunistic and
hospital-acquired infections. Structural mechanisms such as resistance–nodulation–division …

Novel Molecular Markers Linked to Pseudomonas aeruginosa Epidemic High-Risk Clones

W Nageeb, DH Amin, ZM Mohammedsaleh… - Antibiotics, 2021 - mdpi.com
The population structure of Pseudomonas aeruginosa is panmictic-epidemic in nature, with
the prevalence of some high-risk clones. These clones are often linked to virulence …