[HTML][HTML] Anatomical basis of drug delivery to the inner ear
The isolated anatomical position and blood-labyrinth barrier hampers systemic drug delivery
to the mammalian inner ear. Intratympanic placement of drugs and permeation via the round …
to the mammalian inner ear. Intratympanic placement of drugs and permeation via the round …
Models of cochlea used in Cochlear implant research: a review
F Hrncirik, I Roberts, I Sevgili, C Swords… - Annals of Biomedical …, 2023 - Springer
As the first clinically translated machine-neural interface, cochlear implants (CI) have
demonstrated much success in providing hearing to those with severe to profound hearing …
demonstrated much success in providing hearing to those with severe to profound hearing …
[HTML][HTML] Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo
A low dose of 1 μg rhBMP-2 was immobilised by four different functionalising techniques on
recently developed poly (l-lactide)-co-(ε-caprolactone)[(poly (LLA-co-CL)] scaffolds. It was …
recently developed poly (l-lactide)-co-(ε-caprolactone)[(poly (LLA-co-CL)] scaffolds. It was …
Finite element analysis and three-dimensional reconstruction of tonotopically aligned human auditory fiber pathways: a computational environment for modeling …
The application of cochlear implants can be studied with computational models. The
electrical potential distribution induced by an implanted device is evaluated with a volume …
electrical potential distribution induced by an implanted device is evaluated with a volume …
[HTML][HTML] Single-incision cochlear implantation and hearing evaluation in piglets and minipigs
Objectives Various animal models have been established and applied in hearing research.
In the exploration of novel cochlear implant developments, mainly rodents have been used …
In the exploration of novel cochlear implant developments, mainly rodents have been used …
An ovine model for exclusive endoscopic ear surgery
L Anschuetz, M Bonali, M Ghirelli… - … –Head & Neck …, 2017 - jamanetwork.com
Importance With the international spread of exclusive transcanal endoscopic ear surgery,
the need for a suitable and affordable surgical training model has grown during the past …
the need for a suitable and affordable surgical training model has grown during the past …
Sirolimus-eluting cobalt–chrome alloy stent suppresses stent-induced tissue hyperplasia in a porcine Eustachian tube model
Various preclinical studies with developed Eustachian tube (ET) stents are in progress but
have not yet been clinically applied. ET stent is limited by stent-induced tissue hyperplasia in …
have not yet been clinically applied. ET stent is limited by stent-induced tissue hyperplasia in …
Sheep as a Large-Animal Model for Otology Research: Temporal Bone Extraction and Transmastoid Facial Recess Surgical Approach
Purpose Sheep are used as a large-animal model for otology research and can be used to
study implantable hearing devices. However, a method for temporal bone extraction in …
study implantable hearing devices. However, a method for temporal bone extraction in …
The ovine cerebral venous system: comparative anatomy, visualization, and implications for translational research
A Hoffmann, MH Stoffel, B Nitzsche, D Lobsien… - PLoS …, 2014 - journals.plos.org
Cerebrovascular diseases are significant causes of death and disability in humans.
Improvements in diagnostic and therapeutic approaches strongly rely on adequate …
Improvements in diagnostic and therapeutic approaches strongly rely on adequate …
The ovine motor cortex: a review of functional mapping and cytoarchitecture
In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological
research due to their relatively large brain and blood vessel size, their cortical architecture …
research due to their relatively large brain and blood vessel size, their cortical architecture …