[HTML][HTML] Vaccine-associated enhanced disease: case definition and guidelines for data collection, analysis, and presentation of immunization safety data

FM Munoz, JP Cramer, CL Dekker, MZ Dudley… - Vaccine, 2021 - Elsevier
Abstract This is a Brighton Collaboration Case Definition of the term “Vaccine Associated
Enhanced Disease” to be utilized in the evaluation of adverse events following …

Immunopathology of RSV: an updated review

HC Bergeron, RA Tripp - Viruses, 2021 - mdpi.com
RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has
limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding …

Viral and host factors in human respiratory syncytial virus pathogenesis

PL Collins, BS Graham - Journal of virology, 2008 - Am Soc Microbiol
Human respiratory syncytial virus (RSV) was first isolated in 1956 from a laboratory
chimpanzee with upper respiratory tract disease (for general reviews, see references 21, 57 …

Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

MF Delgado, S Coviello, AC Monsalvo, GA Melendi… - Nature medicine, 2009 - nature.com
Respiratory syncytial virus (RSV) is a leading cause of hospitalization in infants. A formalin-
inactivated RSV vaccine was used to immunize children and elicited nonprotective …

CD8 T cell responses to infectious pathogens

P Wong, EG Pamer - Annual review of immunology, 2003 - annualreviews.org
CD8 T cells respond to viral infections but also participate in defense against bacterial and
protozoal infections. In the last few years, as new methods to accurately quantify and …

Viral load drives disease in humans experimentally infected with respiratory syncytial virus

JP DeVincenzo, T Wilkinson, A Vaishnaw… - American journal of …, 2010 - atsjournals.org
Rationale: Respiratory syncytial virus (RSV) is the leading cause of childhood lower
respiratory infection, yet viable therapies are lacking. Two major challenges have stalled …

A role for immune complexes in enhanced respiratory syncytial virus disease

FP Polack, MN Teng, P L. Collins, GA Prince… - The Journal of …, 2002 - rupress.org
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral pneumonia in
infants and young children. Administration of a formalin inactivated vaccine against RSV to …

Inhibition of tumor necrosis factor reduces the severity of virus‐specific lung immunopathology

T Hussell, A Pennycook… - European journal of …, 2001 - Wiley Online Library
TNF antagonists are effective treatments for rheumatoid arthritis and Crohn′ s disease, and
have been tried with variable success in other diseases caused by immune damage. To test …

Immune responses and disease enhancement during respiratory syncytial virus infection

PJM Openshaw, JS Tregoning - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is one of the commonest and most troublesome viruses of
infancy. It causes most cases of bronchiolitis, which is associated with wheezing in later …

Respiratory syncytial virus

CB Hall - Principles and practice of clinical virology, 1999 - Wiley Online Library
Respiratory synctial virus (RSV) infections are a common and concerning conundrum. This
ubiquitous agent is the major respiratory pathogen of young children, with life‐threatening …