The chemistry and biology of vanadium compounds in cancer therapeutics

E Kioseoglou, S Petanidis, C Gabriel… - Coordination Chemistry …, 2015 - Elsevier
A diverse spectrum of vanadium compounds have arisen, over the past years, as potential
therapeutic agents for the treatment of malignancies. Poised to delineate the role of that …

Vanadium, ruthenium and copper compounds: a new class of nonplatinum metallodrugs with anticancer activity

I Esteban Leon… - Current medicinal …, 2017 - ingentaconnect.com
Cancer is a group of diseases involving abnormal cell growth. The cells grow uncontrollably
with the potential to invade and spread to other parts of the body. This disease is one of the …

Medicinal applications of vanadium complexes with Schiff bases

K Hashmi, S Gupta, A Siddique, T Khan… - Journal of Trace Elements …, 2023 - Elsevier
Many transition metal complexes have been explored for their therapeutic properties after
the discovery of cisplatin. Schiff bases have an efficient complexation tendency with the …

Vanadium compounds as PTP inhibitors

E Irving, AW Stoker - Molecules, 2017 - mdpi.com
Phosphotyrosine signaling is regulated by the opposing actions of protein tyrosine kinases
(PTKs) and protein tyrosine phosphatases (PTPs). Here we discuss the potential of …

Stabilities and biological activities of vanadium drugs: what is the nature of the active species?

A Levina, PA Lay - Chemistry–An Asian Journal, 2017 - Wiley Online Library
Diverse biological activities of vanadium (V) drugs mainly arise from their abilities to inhibit
phosphatase enzymes and to alter cell signaling. Initial interest focused on anti‐diabetic …

Oxovanadium (IV) complexes with tetradentate thiosemicarbazones. Synthesis, characterization, anticancer enzyme inhibition and in vitro cytotoxicity on breast cancer …

O Ertik, FD Kalındemirtaş, B Kaya, R Yanardag… - Polyhedron, 2021 - Elsevier
Five oxovanadium (IV) complexes were synthesized using acetyl-and benzoylacetone-S-
alkyl-thiosemicarbazones (alkyl= methyl, ethyl, propyl or butyl) and salicylaldehyde …

Therapeutic potential of a pyridoxal‐based vanadium (IV) complex showing selective cytotoxicity for cancer versus healthy cells

M Strianese, A Basile, A Mazzone… - Journal of Cellular …, 2013 - Wiley Online Library
Vanadium compounds can exert anticancer effects, partly due to inhibition of tyrosine
phosphatases. Here, we report the effect of N, N′‐ethylenebis (pyridoxylideneiminato) …

[HTML][HTML] Antiplatelet aggregation activity of walnut hull extract via suppression of reactive oxygen species generation and caspase activation

A Meshkini, M Tahmasbi - Journal of acupuncture and meridian studies, 2017 - Elsevier
Walnut hull (wal hull) is an agricultural by-product that is widely used in traditional medicine
for alleviating pain and treating skin diseases, however, recently it has gained much …

Highly cytotoxic vanadium (V) complexes of salan ligands; insights on the role of hydrolysis

L Reytman, O Braitbard, EY Tshuva - Dalton Transactions, 2012 - pubs.rsc.org
Vanadium (V) oxo complexes with tetradentate diamine bis (phenolato)“salan” ligands of the
type LVO (OiPr)(L is salan) with different steric and electronic substitutions at the ortho and …

N/N Bridge Type and Substituent Effects on Chemical and Crystallographic Properties of Schiff-Base (Salen/Salphen) Niii Complexes

CS Novoa-Ramírez, A Silva-Becerril… - Crystals, 2020 - mdpi.com
In total, 13 ligands R-salen (N, N'-bis (5-R-salicylidene) ethylenediamine (where R= MeO,
Me, OH, H, Cl, Br, NO2) and R-salphen (N, N'-bis (5-R-salicylidene)-1, 2-phenylenediamine …