Influenza virus infections are a major public health concern and cause significant morbidity
and mortality worldwide. Current influenza virus vaccines are an effective countermeasure …

Dendrimers are drug delivery systems that are characterized by a three-dimensional, star-
shaped, branched macromolecular network. They possess ideal properties such as low …

Vaccines have had broad medical impact, but existing vaccine technologies and production
methods are limited in their ability to respond rapidly to evolving and emerging pathogens …

Pathogenic H7N9 avian influenza viruses continue to represent a public health concern, and
several candidate vaccines are currently being developed. It is vital to assess if protective …

In the early spring of 2013, Chinese health authorities reported several cases of H7N9
influenza virus infections in humans. Since then the virus has established itself at the human …

Importance Human infections with the avian influenza A (H7N9) virus were first reported in
China in 2013 and continue to occur. Hemagglutinin H7 administered alone is a poor …

There is a need for improved influenza vaccines. In this study we compared the antibody
responses in humans after vaccination with an AS03-adjuvanted versus nonadjuvanted …

The innate immune system represents the first line of defense against influenza viruses,
which cause severe inflammation of the respiratory tract and are responsible for more than …

The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine
efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer …

Abstract Development of an effective vaccine against Ebola virus is of high priority. However,
knowledge about potential correlates of protection and the durability of immune response …