Digital twin in healthcare: Recent updates and challenges

T Sun, X He, Z Li - Digital Health, 2023 - journals.sagepub.com
As simulation is playing an increasingly important role in medicine, providing the individual
patient with a customised diagnosis and treatment is envisaged as part of future precision …

Computational models in cardiology

SA Niederer, J Lumens, NA Trayanova - Nature reviews cardiology, 2019 - nature.com
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

The 'Digital Twin'to enable the vision of precision cardiology

J Corral-Acero, F Margara, M Marciniak… - European heart …, 2020 - academic.oup.com
Providing therapies tailored to each patient is the vision of precision medicine, enabled by
the increasing ability to capture extensive data about individual patients. In this position …

[HTML][HTML] Computational fluid dynamics modelling in cardiovascular medicine

PD Morris, A Narracott, H von Tengg-Kobligk… - Heart, 2016 - heart.bmj.com
This paper reviews the methods, benefits and challenges associated with the adoption and
translation of computational fluid dynamics (CFD) modelling within cardiovascular medicine …

Multiphysics and multiscale modelling, data–model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics

R Chabiniok, VY Wang… - Interface …, 2016 - royalsocietypublishing.org
With heart and cardiovascular diseases continually challenging healthcare systems
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …

Verification of cardiac tissue electrophysiology simulators using an N-version benchmark

SA Niederer, E Kerfoot, AP Benson… - … of the Royal …, 2011 - royalsocietypublishing.org
Ongoing developments in cardiac modelling have resulted, in particular, in the development
of advanced and increasingly complex computational frameworks for simulating cardiac …

Patient-specific cardiovascular computational modeling: diversity of personalization and challenges

RA Gray, P Pathmanathan - Journal of cardiovascular translational …, 2018 - Springer
Patient-specific computer models have been developed representing a variety of aspects of
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …

Patient-specific models of cardiac biomechanics

A Krishnamurthy, CT Villongco, J Chuang… - Journal of computational …, 2013 - Elsevier
Patient-specific models of cardiac function have the potential to improve diagnosis and
management of heart disease by integrating medical images with heterogeneous clinical …

[HTML][HTML] Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model

A Neic, FO Campos, AJ Prassl, SA Niederer… - Journal of computational …, 2017 - Elsevier
Anatomically accurate and biophysically detailed bidomain models of the human heart have
proven a powerful tool for gaining quantitative insight into the links between electrical …

[HTML][HTML] 3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics

R Piersanti, F Regazzoni, M Salvador, AF Corno… - Computer Methods in …, 2022 - Elsevier
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …