Estradiol, either from peripheral or central origin, activates multiple molecular
neuroprotective and neuroreparative responses that, being mediated by estrogen receptors …

The Wnt/β-catenin or Wnt canonical pathway controls multiple biological processes
throughout development and adult life. Growing evidences have suggested that …

17β-estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2
is known to be made in neurons in the brain, but its precise functions in the brain are …

Expression of the 17β-estradiol (E2) synthesis enzyme aromatase is highly upregulated in
astrocytes following brain injury. However, the precise role of astrocyte-derived E2 in the …

17β-Estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2
is known to be made in neurons in the brain, but the functions of neuron-derived E2 in the …

Background The steroid hormone estrogen (17-β-estradiol, E2) provides neuroprotection
against cerebral ischemic injury by activating estrogen receptors. The novel estrogen …

Beta amyloid (Aβ) is well accepted to play a central role in the pathogenesis of Alzheimer's
disease (AD). The present work evaluated the therapeutic effects of low-level laser …

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. After the
initial primary mechanical injury, a complex secondary injury cascade involving oxidative …

17β‐Estradiol (E2) is a well‐known neuroprotective factor in the brain. Recently, our lab
demonstrated that the neuroprotective and cognitive effects of E2 require mediation by the …

Hypothermia is currently the only approved therapy for global cerebral ischemia (GCI) after
cardiac arrest; however, it unfortunately has multiple adverse effects. As a noninvasive …