Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …

Spinal cord injury (SCI) is a destructive neurological and pathological state that causes
major motor, sensory and autonomic dysfunctions. Its pathophysiology comprises acute and …

Traumatic spinal cord injury (SCI) triggers a neuro-inflammatory response dominated by
tissue-resident microglia and monocyte derived macrophages (MDMs). Since activated …

Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Neurons of the mammalian central nervous system fail to regenerate. Substantial progress
has been made toward identifying the cellular and molecular mechanisms that underlie …

Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below
the injured segment of the spinal cord, which significantly impacts the quality of life in …

Since no approved therapies to restore mobility and sensation following spinal cord injury
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …

Deficits in neuronal function are a hallmark of spinal cord injury (SCI) and therapeutic efforts
are often focused on central nervous system (CNS) axon regeneration. However, secondary …

Spinal cord injury (SCI) lesions present diverse challenges for repair strategies.
Anatomically complete injuries require restoration of neural connectivity across lesions …