RNA structural dynamics as captured by molecular simulations: a comprehensive overview

J Sponer, G Bussi, M Krepl, P Banáš, S Bottaro… - Chemical …, 2018 - ACS Publications
With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …

[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Supramolecular amphiphiles based on host–guest molecular recognition motifs

G Yu, K Jie, F Huang - Chemical reviews, 2015 - ACS Publications
Self-assembly, which makes use of molecules rather than atomic units, offers a bottom-up
approach to the construction of new materials on multiple length scales.(1-9) By precisely …

Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Advancement of the emerging field of RNA nanotechnology

D Jasinski, F Haque, DW Binzel, P Guo - ACS nano, 2017 - ACS Publications
The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …

Single-stranded DNA and RNA origami

D Han, X Qi, C Myhrvold, B Wang, M Dai, S Jiang… - Science, 2017 - science.org
INTRODUCTION Self-folding of an information-carrying polymer into a compact particle with
defined structure and function (for example, folding of a polypeptide into a protein) is …

Bionanoparticles in cancer imaging, diagnosis, and treatment

Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds

T Bose, G Fridkin, C Davidovich, M Krupkin… - Nucleic acids …, 2022 - academic.oup.com
Although the mode of action of the ribosomes, the multi-component universal effective
protein-synthesis organelles, has been thoroughly explored, their mere appearance …

The emerging field of RNA nanotechnology

P Guo - Nature nanotechnology, 2010 - nature.com
Like DNA, RNA can be designed and manipulated to produce a variety of different
nanostructures. Moreover, RNA has a flexible structure and possesses catalytic functions …

A single-stranded architecture for cotranscriptional folding of RNA nanostructures

C Geary, PWK Rothemund, ES Andersen - Science, 2014 - science.org
Artificial DNA and RNA structures have been used as scaffolds for a variety of nanoscale
devices. In comparison to DNA structures, RNA structures have been limited in size, but they …