In recent years, a great deal of attention has been paid to natural compounds due to their
many biological effects. Polyphenols are a class of plant derivatives that have been widely …

Resveratrol is a natural polyphenolic stilbene isolated from various plants, foods and
beverages with a broad spectrum of biological and pharmacological properties through …

Recent findings have demonstrated the aberrant DNA methylation of the Nrf2-Keap1 genes
in human cancers; however, the epigenetic control of this pathway in non-alcoholic fatty liver …

Phytochemicals are an important part of traditional medicine and have been investigated in
detail for possible inclusion in modern medicine as well. These compounds often serve as …

Sulforaphane was reported to exert neuroprotective effects via upregulating expression of
nuclear factor erythroid 2-related factor 2 (Nrf2) and has received increasing attention as an …

Chromatin can adopt a decondensed state linked to gene transcription (euchromatin) and a
condensed state linked to transcriptional repression (heterochromatin). These states are …

Vascular aging is a pivotal risk factor promoting vascular dysfunction, the development and
progression of vascular aging-related diseases. The structure and function of endothelial …

One of the main current strategies for cancer treatment is represented by combination
chemotherapy. More recently, this strategy shifted to the “hybrid strategy”, namely the …

Background: Genomic DNA methylation plays an important role in both the occurrence and
development of bladder cancer. Kaempferol (Kae), a natural flavonoid that is present in …

Cardiovascular disease (CVD) retains a leadership as a major cause of human death
worldwide. Although a substantial progress was attained in the development of …