All solid tumours require a vascular supply in order to progress. Although the ability to
induce angiogenesis (new blood vessel growth) has long been regarded as essential to this …

Magnetic resonance imaging (MRI) is the cornerstone for evaluating patients with brain
masses such as primary and metastatic tumors. Important challenges in effectively detecting …

The immune microenvironment of the brain differs from that of other organs and the role of
tumor-infiltrating lymphocytes (TILs) in brain metastases (BM), one of the most common and …

Aim We provide a descriptive statistical analysis of baseline characteristics and the clinical
course of a large real-life cohort of brain metastases (BM) patients. Methods We performed a …

Background Brain metastases are generally considered to be well demarcated from the
surrounding brain parenchyma, although infiltrative growth patterns have been observed …

Differential diagnosis of brain lesion pathologies is complex, but it is nevertheless crucial for
appropriate clinical management. Advanced imaging methods, including diffusion-weighted …

Aims In this study we aimed to characterize immune infiltrates and expression of
programmed death 1 (PD‐1) and programmed death ligand 1 (PD‐L1) in a series of …

Cancer cells can use existing blood vessels to acquire a vasculature. This process is termed
'vessel co-option'. Vessel co-option is an alternative to the growth of new blood vessels, or …

Background: Brain metastases are associated with poor survival. Molecular genetic testing
informs on targeted therapy and survival. The purpose of this study was to perform a MR …

Brain metastases (BM) are the most serious neurological complication of cancer that results
in significant morbidity and mortality in these patients. The most common primary …