Glucocorticoids are hormones that regulate several functions in living organisms and
synthetic glucocorticoids are the most powerful anti-inflammatory pharmacological tool that …

Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …

Cushing's syndrome (CS), or chronic hypercortisolism, induces a variety of alterations in the
immune system, often leading to severe clinical complications such as sepsis and …

An established body of knowledge and clinical practice has argued in favor of the use of
glucocorticoids in various chronic inflammatory and autoimmune diseases. However, the …

Glucocorticoids (GCs) are the most commonly used drugs for treatment of autoimmune and
inflammatory diseases. Their efficacy is due to their ability to bind cytoplasmic receptors …

Over the last decades, our understanding of adaptive immune responses to solid organ
transplantation increased considerably and allowed development of immunosuppressive …

Annexin A1 is a protein with multifunctional roles in innate and adaptive immunity mainly
devoted to the regulation of inflammatory cells and the resolution of inflammation. Most of …

Glucocorticoid-induced leucine zipper (GILZ) exerts anti-inflammatory effects on the immune
cells. However, less is known about GILZ function in neutrophils. We aimed to define the …

Glomerulonephritis are renal disorders resulting from different pathogenic mechanisms (ie,
autoimmunity, complement, inflammatory activation, etc.). Clarifying details of the pathogenic …

Cardiovascular diseases (CVD) remain the leading cause of mortality worldwide. The main
cause underlying CVD is associated with the pathological remodeling of the vascular wall …