Genome stability is a crucial feature of eukaryotic organisms because its alteration
drastically affects the normal development and survival of cells and the organism as a …

Genetic information typically remains constant in all cells throughout the life cycle of most
organisms. However, there are exceptions where DNA elimination is an integral …

An unusual supernumerary chromosome has been reported for two related avian species,
the zebra and Bengalese finches. This large, germline-restricted chromosome (GRC) is …

In some eukaryotes, germline and somatic genomes differ dramatically in their composition.
Here we characterise a major germline–soma dissimilarity caused by a germline-restricted …

Over the last few decades, an increasing number of vertebrate taxa have been identified that
undergo programmed genome rearrangement, or programmed DNA loss, during …

B chromosomes represent additional chromosomes found in many eukaryotic organisms.
Their origin is not completely understood but recent genomic studies suggest that they …

Most eukaryotes maintain the stability of their cellular genome sizes to ensure genome
transmission to offspring through sexual reproduction. However, some alter their genome …

Developmentally programmed genome rearrangements are rare in vertebrates, but have
been reported in scattered lineages including the bandicoot, hagfish, lamprey, and zebra …

Germline-restricted chromosomes (GRCs) are accessory chromosomes that occur only in
germ cells. They are eliminated from somatic cells through programmed DNA elimination …

Developmentally programmed genome rearrangement accompanies differentiation of the
silent germline micronucleus into the transcriptionally active somatic macronucleus in the …