Adult stem cells at work: regenerating skeletal muscle

M Schmidt, SC Schüler, SS Hüttner, B von Eyss… - Cellular and Molecular …, 2019 - Springer
Skeletal muscle regeneration is a finely tuned process involving the activation of various
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …

An overview of technical considerations for Western blotting applications to physiological research

JJ Bass, DJ Wilkinson, D Rankin… - … journal of medicine …, 2017 - Wiley Online Library
The applications of Western/immunoblotting (WB) techniques have reached multiple layers
of the scientific community and are now considered routine procedures in the field of …

Irisin is a pro-myogenic factor that induces skeletal muscle hypertrophy and rescues denervation-induced atrophy

MM Reza, N Subramaniyam, CM Sim, X Ge… - Nature …, 2017 - nature.com
Exercise induces expression of the myokine irisin, which is known to promote browning of
white adipose tissue and has been shown to mediate beneficial effects following exercise …

Myoblast fusion: lessons from flies and mice

SM Abmayr, GK Pavlath - Development, 2012 - journals.biologists.com
The fusion of myoblasts into multinucleate syncytia plays a fundamental role in muscle
function, as it supports the formation of extended sarcomeric arrays, or myofibrils, within a …

The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation

PA Bilodeau, ES Coyne… - American Journal of …, 2016 - journals.physiology.org
Muscle atrophy complicates many diseases as well as aging, and its presence predicts both
decreased quality of life and survival. Much work has been conducted to define the …

Signaling mechanisms in mammalian myoblast fusion

SM Hindi, MM Tajrishi, A Kumar - Science signaling, 2013 - science.org
Myoblast fusion is a critical process that contributes to the growth of muscle during
development and to the regeneration of myofibers upon injury. Myoblasts fuse with each …

Mechanisms regulating myoblast fusion: A multilevel interplay

L Lehka, MJ Rędowicz - Seminars in cell & developmental biology, 2020 - Elsevier
Myoblast fusion into myotubes is one of the crucial steps of skeletal muscle development
(myogenesis). The fusion is preceded by specification of a myogenic lineage (mesodermal …

CircRNA—Protein Interactions in Muscle Development and Diseases

S Zheng, X Zhang, E Odame, X Xu, Y Chen… - International journal of …, 2021 - mdpi.com
Circular RNA (circRNA) is a kind of novel endogenous noncoding RNA formed through back-
splicing of mRNA precursor. The biogenesis, degradation, nucleus–cytoplasm transport …

The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis

JDR Knight, R Kothary - Skeletal muscle, 2011 - Springer
Myogenesis is a complex and tightly regulated process, the end result of which is the
formation of a multinucleated myofibre with contractile capability. Typically, this process is …

Myomaker is essential for muscle regeneration

DP Millay, LB Sutherland, R Bassel-Duby… - Genes & …, 2014 - genesdev.cshlp.org
Regeneration of injured adult skeletal muscle involves fusion of activated satellite cells to
form new myofibers. Myomaker is a muscle-specific membrane protein required for fusion of …