[HTML][HTML] Amniotic fluid characteristics and its application in stem cell therapy: A review

H Shamsnajafabadi, ZS Soheili - International Journal of …, 2022 - ncbi.nlm.nih.gov
Amniotic fluid (AF) is a clear yellow fluid that surrounds the fetus during pregnancy. The
amniotic sac consists of 2 layers: the amnion and the chorion. Osmotic and hydrostatic …

Chemical and biological molecules involved in differentiation, maturation, and survival of dopaminergic neurons in health and Parkinson's disease: physiological …

G Gaggi, A Di Credico, P Izzicupo, G Iannetti… - Biomedicines, 2021 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative disease
characterized by a specific and progressive loss of dopaminergic (DA) neurons and …

Bisphenols and perfluoroalkyls alter human stem cells integrity: A possible link with infertility

G Gaggi, A Di Credico, F Barbagallo, B Ghinassi… - Environmental …, 2023 - Elsevier
Bisphenols and Perfluoroalkyls are chemical compounds widely used in industry known to
be endocrine disruptors (EDs). Once ingested through contaminated aliments, they mimic …

Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion

E Guerra, V Relli, M Ceci, R Tripaldi, P Simeone… - Oncogene, 2022 - nature.com
Trop-2 is a transmembrane signal transducer that is overexpressed in most human cancers,
and drives malignant progression. To gain knowledge on the higher-order molecular …

The effects of combined exposure to bisphenols and perfluoroalkyls on human perinatal stem cells and the potential Implications for health outcomes

A Di Credico, G Gaggi, I Bucci, B Ghinassi… - International Journal of …, 2023 - mdpi.com
The present study investigates the impact of two endocrine disruptors, namely Bisphenols
(BPs) and Perfluoroalkyls (PFs), on human stem cells. These chemicals leach from plastic …

[HTML][HTML] Metoprolol disrupts inflammatory response of human cardiomyocytes via β-arrestin2 biased agonism and NF-κB signaling modulation

F Ricci, A Di Credico, G Gaggi, G Iannetti… - Biomedicine & …, 2023 - Elsevier
Aims Recent evidence supports non-class cardioprotective effects of metoprolol against
neutrophil-mediated ischemia-reperfusion injury during exacerbated inflammation. Whether …

Human mesenchymal amniotic fluid stem cells reveal an unexpected neuronal potential differentiating into functional spinal motor neurons

G Gaggi, A Di Credico, S Guarnieri… - Frontiers in Cell and …, 2022 - frontiersin.org
Human amniotic fluids stem cells (hAFSCs) can be easily isolated from the amniotic fluid
during routinely scheduled amniocentesis. Unlike hiPSCs or hESC, they are neither …

Spare parts from discarded materials: Fetal annexes in regenerative medicine

G Gaggi, P Izzicupo, A Di Credico, S Sancilio… - International Journal of …, 2019 - mdpi.com
One of the main aims in regenerative medicine is to find stem cells that are easy to obtain
and are safe and efficient in either an autologous or allogenic host when transplanted. This …

Epigenetic features of human perinatal stem cells redefine their stemness potential

G Gaggi, A Di Credico, P Izzicupo, I Antonucci… - Cells, 2020 - mdpi.com
Human perinatal stem cells (SCs) can be isolated from fetal annexes without ethical or
safety limitations. They are generally considered multipotent; nevertheless, their biological …

Decellularized extracellular matrices and cardiac differentiation: study on human amniotic fluid-stem cells

G Gaggi, A Di Credico, P Izzicupo, S Sancilio… - International Journal of …, 2020 - mdpi.com
Cell therapy with a variety of stem populations is increasingly being investigated as a
promising regenerative strategy for cardiovascular (CV) diseases. Their combination with …