Hepatorenal syndrome: pathophysiology, diagnosis, and management

DA Simonetto, P Gines, PS Kamath - bmj, 2020 - bmj.com
Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

Liver cirrhosis

P Ginès, A Krag, JG Abraldes, E Solà, N Fabrellas… - The Lancet, 2021 - thelancet.com
Cirrhosis is widely prevalent worldwide and can be a consequence of different causes, such
as obesity, non-alcoholic fatty liver disease, high alcohol consumption, hepatitis B or C …

Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: 2021 practice guidance by the American Association …

SW Biggins, P Angeli, G Garcia‐Tsao, P Ginès… - …, 2021 - Wiley Online Library
This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

P Angeli, M Bernardi, C Villanueva, C Francoz… - Journal of …, 2018 - Elsevier
The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis

G Mezzano, A Juanola, A Cardenas, E Mezey… - Gut, 2022 - gut.bmj.com
Background and aims Acute-on-chronic liver failure (ACLF) is characterised by acute
decompensation of cirrhosis associated with organ failures. We systematically evaluated the …

[PDF][PDF] Neutrophil gelatinase‐associated lipocalin for assessment of acute kidney injury in cirrhosis: a prospective study

P Huelin, E Solà, C Elia, C Solé, A Risso… - …, 2019 - Wiley Online Library
Kidney biomarkers appear to be useful in differential diagnosis between acute tubular
necrosis (ATN) and other types of acute kidney injury (AKI) in cirrhosis, particularly …

[HTML][HTML] Urinary NGAL as a diagnostic and prognostic marker for acute kidney injury in cirrhosis: a prospective study

AS Allegretti, XV Parada, P Endres… - Clinical and …, 2021 - journals.lww.com
METHODS: Urinary NGAL was measured in a prospective cohort of 213 US hospitalized
patients with decompensated cirrhosis (161 with AKI and 52 reference patients without AKI) …

Diagnostic and prognostic performance of urinary neutrophil Gelatinase‐Associated Lipocalin in patients with cirrhosis and acute kidney injury

C Gambino, S Piano, M Stenico, M Tonon, A Brocca… - Hepatology, 2023 - journals.lww.com
Diagnostic and prognostic performance of urinary neutrophil... : Hepatology Diagnostic and
prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with …

Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US

KR Patidar, JM Belcher, KR Regner, SAS Hillien… - Journal of …, 2023 - Elsevier
Background & Aims Acute kidney injury (AKI) in cirrhosis is common and associated with
high morbidity, but the incidence rates of different etiologies of AKI are not well described in …

Hepatorenal syndrome

P Ginès, E Solà, P Angeli, F Wong, MK Nadim… - Nature Reviews …, 2018 - nature.com
Hepatorenal syndrome (HRS) is a form of kidney function impairment that characteristically
occurs in cirrhosis. Recent changes in terminology have led to acute HRS being referred to …