Epilepsy is a chronic disease of the central nervous system characterized by recurrent
epileptic seizures. As a result of epileptic seizure or status epilepticus oxidants are …

Epilepsy is a common neurological disorder that is primarily treated with antiseizure
medications (ASMs). Although dozens of ASMs are available in the clinic, approximately …

Introduction Guidelines recommend a number of pharmacotherapeutic options used as
monotherapy or in combination with others for treating the pain of trigeminal neuropathy …

Levetiracetam (LEV) is an anti‐epileptic drug approved for use in various populations. The
pharmacokinetic (PK) behavior of LEV may be altered in the elderly and patients with renal …

The nervous system is important, because it regulates the physiological function of the body.
Neurons are the most basic structural and functional unit of the nervous system. The …

The review presents data from the last few years on bioanalytical methods used in
therapeutic drug monitoring (TDM) of the 1st–3rd generation and the newest antiepileptic …

Epilepsy is a common neurological disorder that is mainly treated using antiepileptic drugs.
Several antiepileptic drugs such as phenobarbital, phenytoin, primidone, and ethosuximide …

Objective To compare the efficacy and safety of Levetiracetam (LEV) and Oxcarbazepine
(OXC) as monotherapy for the treatment of newly diagnosed focal epilepsy. Methods We …

Objectives To develop an isotope dilution-liquid chromatography-tandem mass spectrometry
(LC-MS/MS)-based candidate reference measurement procedure (RMP) for levetiracetam …

Epilepsy, a recurrent neurological disorder involving abnormal neurotransmitter kinetics in
the brain, has emerged as a global health concern. The mechanism of epileptic seizures is …