The remarkable diversity of specialized metabolites produced by plants has inspired several
decades of research and nucleated a long list of theories to guide empirical ecological …

The CCCTC-binding factor (CTCF) works together with the cohesin complex to drive the
formation of chromatin loops and topologically associating domains, but its role in gene …

Plants produce a great number of phytochemicals serving a variety of different functions.
Recently, the chemodiversity of these compounds (ie, the diversity of compounds produced …

Most mammalian genes produce multiple distinct messenger RNAs through alternative
splicing, but the extent of splicing conservation is not clear. To assess tissue-specific …

Although much is known about plant traits that function in nonhost resistance against
pathogens, little is known about nonhost resistance against herbivores, despite its …

Divergence of cis-regulatory elements drives species-specific traits, but how this manifests in
the evolution of the neocortex at the molecular and cellular level remains unclear. Here we …

Senescent cells affect many physiological and pathophysiological processes. While select
genetic and epigenetic elements for senescence induction have been identified, the …

Abstract Background Aberrant CpG island promoter DNA hypermethylation is frequently
observed in cancer and is believed to contribute to tumor progression by silencing the …

The diversity of life on Earth is a result of continual innovations in molecular networks
influencing morphology and physiology. Plant specialized metabolism produces hundreds …

Background Animal-derived elicitors can be used by plants to detect herbivory but they
function only in specific insect–plant interactions. How can plants generally perceive …