Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …

Abstract Objectives Meglumine antimoniate (MA; Glucantime®), the 80‐year‐old first‐line
systemic treatment for all forms of American tegumentary leishmaniasis (ATL) caused by …

Leishmania RNA virus (LRV) is an important virulence factor associated with the
development of mucocutaneous Leishmaniasis, a severe form of the disease. LRV-mediated …

The pervasiveness of viral infectious agents, capable of parasitizing living organisms all
along the evolutionary spectrum, has obligated hosts to evolve defense mechanisms that …

Animal microbiomes influence their development, behavior and interactions with other
organisms. Parasitic metazoans also harbor microbial communities; although they are likely …

The description of the genus Leishmania as the causative agent of leishmaniasis occurred
in the modern age. However, evolutionary studies suggest that the origin of Leishmania can …

Until universal influenza vaccines become available, pandemic preparedness should
include developing classical vaccines against potential pandemic influenza subtypes. We …

Parasitic flatworms (Neodermata) infect all vertebrates and represent a significant health
and economic burden worldwide due to the debilitating diseases they cause. This study …

The endogenous double-stranded RNA (dsRNA) virus Leishmaniavirus (LRV1) has been
implicated as a pathogenicity factor for leishmaniasis in rodent models and human disease …

Leishmaniaviruses (LRVs) have been demonstrated to enhance progression of
leishmaniasis, a vector-transmitted disease with a wide range of clinical manifestations that …