Advances in acute myeloid leukemia

LF Newell, RJ Cook - Bmj, 2021 - bmj.com
Acute myeloid leukemia (AML) is an uncommon but potentially catastrophic diagnosis with
historically high mortality rates. The standard of care treatment remained unchanged for …

Myelodysplastic syndromes: 2023 update on diagnosis, risk‐stratification, and management

G Garcia‐Manero - American journal of hematology, 2023 - Wiley Online Library
Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

C Toffalori, L Zito, V Gambacorta, M Riba, G Oliveira… - Nature medicine, 2019 - nature.com
Transplantation of hematopoietic cells from a healthy individual (allogeneic hematopoietic
cell transplantation (allo-HCT)) demonstrates that adoptive immunotherapy can cure blood …

A phase 3 randomized study of 5-azacitidine maintenance vs observation after transplant in high-risk AML and MDS patients

B Oran, M de Lima, G Garcia-Manero, PF Thall… - Blood …, 2020 - ashpublications.org
This study investigated the efficacy and safety of azacitidine maintenance in the
posttransplant setting based on the encouraging phase 1/2 reports for azacitidine …

Acute myeloid leukemia

H Döhner, DJ Weisdorf… - New England Journal of …, 2015 - Mass Medical Soc
Acute Myeloid Leukemia | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

T De Witte, D Bowen, M Robin… - Blood, The Journal …, 2017 - ashpublications.org
An international expert panel, active within the European Society for Blood and Marrow
Transplantation, European LeukemiaNet, Blood and Marrow Transplant Clinical Trial Group …

Hematopoietic stem cell transplantation for patients with AML in first complete remission

JJ Cornelissen, D Blaise - Blood, The Journal of the American …, 2016 - ashpublications.org
Postremission therapy in patients with acute myeloid leukemia (AML) may consist of
continuing chemotherapy or transplantation using either autologous or allogeneic stem …

Acute myeloid leukemia: 2014 Update on risk‐stratification and management

EH Estey - American journal of hematology, 2014 - Wiley Online Library
Overview: Evidence suggest that even patients aged 70 or above benefit from specific AML
therapy. The fundamental decision in AML then becomes whether to recommend standard …

Myelodysplastic syndromes: 2018 update on diagnosis, risk‐stratification and management

G Montalban‐Bravo… - American journal of …, 2018 - Wiley Online Library
Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

How I treat extramedullary acute myeloid leukemia

RL Bakst, MS Tallman, D Douer… - Blood, The Journal of …, 2011 - ashpublications.org
Extramedullary (EM) manifestations of acute leukemia include a wide variety of clinically
significant phenomena that often pose therapeutic dilemmas. Myeloid sarcoma (MS) and …