The heart pumps blood to maintain circulation and ensure the delivery of oxygenated blood
to all the organs of the body. Mechanics play a critical role in governing and regulating heart …

Although computational modeling is common in many areas of science and engineering,
only recently have advances in experimental techniques and medical imaging allowed this …

Background—The present study examined whether transplantation of adherent bone
marrow–derived stem cells, termed pMultistem, induces neovascularization and …

Objectives: This study tests the hypothesis that hypocontractile, borderzone myocardium
adjacent to an expanding infarct becomes progressively larger and more hypocontractile as …

Tagged MRI and finite-element (FE) analysis are valuable tools in analyzing cardiac
mechanics. To determine systolic material parameters in three-dimensional stress-strain …

Ventricular wall stress is believed to be responsible for many physical mechanisms taking
place in the human heart, including ventricular remodeling, which is frequently associated …

A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart
having a pathological condition. The method includes identifying a target region of the …

Bogen DK. Rabinowitz SA. Needleman A. McMahon TA, Abelmann WH. An analysis of
myocardial infarction. The effect of regional changes in contractility. Circ Res 1984: 55: 805 …

BACKGROUND: Left ventricular remodeling after posterobasal myocardial infarction can
lead to ischemic mitral regurgitation. This occurs as a consequence of leaflet tethering due …

Predictive computational modeling has revolutionized classical engineering disciplines and
is in the process of transforming cardiovascular research. This is particularly relevant for …