The consequences of human adenovirus (HAdV) infections are generally mild. However,
despite the perception that HAdVs are harmless, infections can cause severe disease in …

Abstract Adenovirus (AdV)'virus-associated'RNAs (VA RNAs) are exceptionally abundant
(up to 10 8 copies/cell), heterogeneous, non-coding RNA transcripts (∼ 150–200 …

We used the Nanopore long-read sequencing platform to demonstrate how amazingly
complex the human adenovirus type 2 (Ad2) transcriptome is, with a flexible splicing …

Human adenoviruses (HAdVs) are common pathogens causing a variety of respiratory,
ocular and gastrointestinal diseases. To accomplish their efficient replication, HAdVs take an …

Virus infected immune cells can rapidly respond to the invader by activating the
inflammasome and as a consequence release proinflammatory cytokines and eventually die …

The adenovirus (Ad) serotype 5 genome encodes two noncoding small RNAs (virus-
associated RNAs I and II [VA-RNAI and-II]), which are approximately 160-nucleotide (nt) …

During infection, adenoviruses inhibit the cellular RNA interference (RNAi) machinery by
saturating the RNA-induced silencing complex (RISC) of the host cells with large amounts of …

Oncolytic adenoviruses are in development as immunotherapeutic agents for solid tumors.
Their efficacy is in part dependent on their ability to replicate in tumors. It is, however, difficult …

Abstract RNA helicase A (RHA) is a ubiquitously expressed DExH-box helicase enzyme that
is involved in a wide range of biological processes including transcription, translation, and …

Human adenoviruses (HAdVs) are common pathogens associated with a wide variety of
respiratory, ocular, and gastrointestinal diseases. To achieve its effective lytic mode of …