Over 70% of Americans take some form of dietary supplement every day, and the
supplement industry is currently big business, with a gross of over $28 billion. However …

Male germ cells, the repository cells of the genome, comprise several successive
developmental stages starting in the embryo and ending up with the spermatozoon …

The Leydig cells of the testis have the capacity to biosynthesize testosterone from
cholesterol. Testosterone and its metabolically activated product dihydrotestosterone are …

During the past decades, a large body of information concerning the effects of endocrine
disrupting compounds (EDCs) on animals and humans has been accumulated. EDCs are of …

The steroidogenic cells in the testicle, Leydig cells, located in the interstitial compartment,
play a vital role in male reproductive tract development, maintenance of proper …

Isoflavones are a group of secondary metabolites found in plants belonging to the class of
phytoestrogens. These, because they have a chemical structure similar to the endogenous …

Phytoestrogens are a family of diverse polyphenolic compounds derived from nature plant
that structurally or functionally mimic circulating estrogen in the mammalian reproductive …

Soy infant formula contains soy protein isolates and is fed to infants as a supplement to or
replacement for human milk or cow milk. Soy protein isolates contains estrogenic …

Soy and soy-based products are widely consumed by infants and adult individuals. There
has been speculation that the presence of isoflavone phytoestrogens in soybean cause …

The present study investigated if Aflatoxin B 1 (AFB 1), a potent and naturally occurring
mycotoxin, interferes with the steroidogenic pathway in rat Leydig cells. Testicular Leydig …