Sex and gender in neurodevelopmental conditions

S Bölte, J Neufeld, PB Marschik, ZJ Williams… - Nature Reviews …, 2023 - nature.com
Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered …

Biological hypotheses, risk factors, and biomarkers of schizophrenia

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium

DB Dwyer, GB Chand, A Pigoni, A Khuntia, J Wen… - Molecular …, 2023 - nature.com
Using machine learning, we recently decomposed the neuroanatomical heterogeneity of
established schizophrenia to discover two volumetric subgroups—a 'lower brain …

D2/3 agonist during learning potentiates cued risky choice

L Mortazavi, TJ Hynes, CS Chernoff… - Journal of …, 2023 - Soc Neuroscience
Impulse control and/or gambling disorders can be triggered by dopamine agonist therapies
used to treat Parkinson9s disease, but the cognitive and neurobiological mechanisms …

Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

MS Lafta, J Mwinyi, O Affatato, G Rukh… - Frontiers in …, 2024 - frontiersin.org
Increased knowledge about sex differences is important for development of individualized
treatments against many diseases as well as understanding behavioral and pathological …

Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function

MC Gulfo, JJ Lebowitz, C Ramos… - Proceedings of the …, 2023 - National Acad Sciences
Hilar mossy cells (MCs) are principal excitatory neurons of the dentate gyrus (DG) that play
critical roles in hippocampal function and have been implicated in brain disorders such as …

Diazepam at environmentally relevant concentrations disturbed social interactions and brain neurotransmitters in adult Japanese medaka (Oryzias latipes)

X Qiu, S Wang, M Zhuo, Y Shi, K Chen - Aquatic Toxicology, 2023 - Elsevier
Pollution by diazepam (DZP) is increasingly recognized as a major threat to aquatic
organisms, but knowledge about its potential risk to fish is still limited. In this study, we …

A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions

S Kouhnavardi, A Ecevitoglu, V Dragačević, F Sanna… - Biomolecules, 2022 - mdpi.com
Dopamine (DA), the most abundant human brain catecholaminergic neurotransmitter,
modulates key behavioral and neurological processes in young and senescent brains …

A sex difference in mouse dopaminergic projections from the midbrain to basolateral amygdala

MTC Manion, ER Glasper, KH Wang - Biology of sex differences, 2022 - Springer
Background Dopaminergic circuits play important roles in the motivational control of
behavior and dysfunction in dopaminergic circuits have been implicated in several …

Attention-deficit/hyperactivity disorder and the menstrual cycle: Theory and evidence

AG Eng, U Nirjar, AR Elkins, YJ Sizemore… - Hormones and …, 2024 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that
exhibits striking sex differences in symptoms, prevalence, and associated problems across …