Sexual dimorphism in colon cancer

M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …

[HTML][HTML] Chromatin modifiers–Coordinators of estrogen action

AA Rawłuszko-Wieczorek, K Romanowska… - Biomedicine & …, 2022 - Elsevier
A group of hormones, called estrogens, are pivotal drivers of various physiological
processes. Expectedly, estrogen-driven actions are also relevant modulators of …

Metabolic modeling of host–microbe interactions for therapeutics in colorectal cancer

P Bhalla, R Rengaswamy, D Karunagaran… - NPJ systems biology …, 2022 - nature.com
The onset of colorectal cancer (CRC) is often attributed to gut bacterial dysbiosis, and thus
gut microbiota are highly relevant in devising treatment strategies. Certain gut microbes, like …

[HTML][HTML] Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males

AA Mahbub, A Aslam, ME Elzubier… - Frontiers in …, 2022 - frontiersin.org
Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …

[HTML][HTML] Estrogen receptor β affects hypoxia response in colorectal cancer cells

AA Rawłuszko-Wieczorek, J Lipowicz… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The occurrence of colorectal cancer (CRC) is inversely correlated with estrogen receptor
beta (ERβ) presence. Additionally, multiple studies associate low ERβ expression with …

Estrogen concentration and estrogen receptor-β expression in postmenopausal colon cancer considering patient/tumor background

N Honma, T Arai, Y Matsuda, Y Fukunaga… - Journal of Cancer …, 2022 - Springer
Purpose A large number of studies have suggested an inhibitory role of estrogens against
colorectal cancer (CRC), but persistent controversy exists. CRC characteristics are affected …

Multifunctional isotopic standards based steroidomics strategy: Exploration of cancer screening model

Q Zhang, R Liu, H Xu, X Yang, Y Zhang, Q Wang… - … of Chromatography A, 2020 - Elsevier
Quantitative determination of endogenous compounds in biological samples has still been
challenged by the absence of authentic blank matrix. Alternative strategy of surrogate matrix …

Susceptibility to Colorectal Cancer Based on HSD17B4 rs721673 and rs721675 Polymorphisms and Alcohol Intake among Taiwan Biobank Participants: A …

TC Lin, MH Chuang, CN Hsiung, PK Chang… - Journal of Personalized …, 2023 - mdpi.com
Colorectal cancer (CRC) is a major public health issue, and there are limited studies on the
association between 17β-hydroxysteroid dehydrogenase type 4 (HSD17B4) polymorphism …

Evaluation of the epidemiological and prognosis significance of ESR2 rs3020450 polymorphism in ovarian cancer

Y Feng, Z Peng, W Liu, Z Yang, J Shang, L Cui, F Duan - Gene, 2019 - Elsevier
Aim To investigate the correlation between the polymorphism of estrogen receptor β gene
(ESR2) rs3020450 and cancer susceptibility, and explore the epidemiological significance …

Breast cancer in women with diabetes mellitus type 2

TS Vatseba, LK Sokolova - Мир медицины и биологии, 2019 - cyberleninka.ru
Prevalence of breast cancer in the women with diabetes mellitus type 2 and the effect of
hypoglycemic therapy on the frequency of the cancer and survival rates were studied. A …