Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …

Fasciolosis caused by the liver flukes Fasciola hepatica and Fasciola gigantica is one of the
most important neglected parasitic diseases of humans and animals. The ability of the …

Background Mesenchymal stem cell (MSC)-derived exosome administration has been
considered as a novel cell-free therapy for liver diseases through cell-cell communication …

Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …

The vertebrate gut teems with a large, diverse, and dynamic bacterial community that has
pervasive effects on gut physiology, metabolism, and immunity. Under natural conditions …

There is increasing interest in helminth parasite modulation of the immune system, both from
the fundamental perspective of the “arms race” between host and parasite, and equally …

The survival of helminths in the host over long periods of time is the result of a process of
adaptation or dynamic co-evolution between the host and the parasite. However, infection …

Helminths (worms) are one of the most successful organisms in nature given their ability to
infect millions of humans and animals worldwide. Their success can be attributed to their …

Background The major pathogenesis associated with Fasciola hepatica infection results
from the extensive tissue damage caused by the tunnelling and feeding activity of immature …

Diabetes is the fastest growing chronic disease globally, with prevalence increasing at a
faster rate than heart disease and cancer. While the disease presents clinically as chronic …