COVID-19 at a glance: An up-to-date overview on variants, drug design and therapies
D Iacopetta, J Ceramella, A Catalano, C Saturnino… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the
Coronavirus family which caused the worldwide pandemic of human respiratory illness …
Coronavirus family which caused the worldwide pandemic of human respiratory illness …
[HTML][HTML] Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine
L Ye, S Fan, P Zhao, C Wu, M Liu, S Hu, P Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
Dopamine reduces SARS-CoV-2 replication in vitro through downregulation of D2 receptors and upregulation of type-I interferons
F Limanaqi, S Zecchini, B Dino, S Strizzi, G Cappelletti… - Cells, 2022 - mdpi.com
Recent evidence suggests that SARS-CoV-2 hinders immune responses via dopamine (DA)-
related mechanisms. Nonetheless, studies addressing the specific role of DA in the frame of …
related mechanisms. Nonetheless, studies addressing the specific role of DA in the frame of …
Determining similarities of COVID-19–lung cancer drugs and affinity binding mode analysis by graph neural network-based GEFA method
COVID-19 is a worldwide health crisis seriously endangering the arsenal of antiviral and
antibiotic drugs. It is urgent to find an effective antiviral drug against pandemic caused by the …
antibiotic drugs. It is urgent to find an effective antiviral drug against pandemic caused by the …
Instruction of molecular structure similarity and scaffolds of drugs under investigation in ebola virus treatment by atom-pair and graph network: A combination of …
The virus that causes Ebola is fatal. Although many researchers have attempted to contain
this deadly infection, the fatality rate remains high. The atom-pair fingerprint technique was …
this deadly infection, the fatality rate remains high. The atom-pair fingerprint technique was …
Interference of small compounds and Mg2+ with dsRNA-binding fluorophores compromises the identification of SARS-CoV-2 RdRp inhibitors
S Llanos, B Di Geronimo, E Casajús… - Scientific Reports, 2024 - nature.com
The COVID-19 pandemic highlighted the need for the rapid development of antiviral
therapies. Viral RNA-dependent RNA polymerases (RdRp) are promising targets, and …
therapies. Viral RNA-dependent RNA polymerases (RdRp) are promising targets, and …
Mpox Knowledge Graph: a comprehensive representation embedding chemical entities and associated biology of Mpox
The outbreak of Mpox virus (MPXV) infection in May 2022 is declared a global health
emergency by WHO. A total of 84 330 cases have been confirmed as of 5 January 2023 and …
emergency by WHO. A total of 84 330 cases have been confirmed as of 5 January 2023 and …
[HTML][HTML] Network pharmacology and in silico pharmacokinetic prediction of Ozanimod in the management of ulcerative colitis: A computational study
P Sivasakthi, S Sabarathinam… - Health Science …, 2022 - ncbi.nlm.nih.gov
3. METHOD The pharmacokinetic profile of OZM was observed from the PKCSM online
server. Pass online tool is used to predict the biological activity profile of the compound …
server. Pass online tool is used to predict the biological activity profile of the compound …
Are the Current Processes and Regulations Fit for Purpose to Deliver Novel Therapies During Pandemics? A Perspective on COVID-19 from the UK
R Jandu, C Naraynassamy, N Sreeharan - Pharmaceutical Medicine, 2022 - Springer
The COVID-19 pandemic was the first 'stress test'to assess whether the current regulations
in the United Kingdom (UK) are fit for purpose to develop novel therapies during pandemics …
in the United Kingdom (UK) are fit for purpose to develop novel therapies during pandemics …
Monkeypox Knowledge Graph: A comprehensive representation embedding chemical entities and associated biology of Monkeypox
The outbreak of Monkeypox virus (MPXV) infection in May 2022 is declared a global health
emergency by WHO. As of 28th July, 21067 cases have been confirmed and the numbers …
emergency by WHO. As of 28th July, 21067 cases have been confirmed and the numbers …