Helicobacter pylori: gastric cancer and beyond

DB Polk, RM Peek Jr - Nature reviews cancer, 2010 - nature.com
Helicobacter pylori is the dominant species of the human gastric microbiome, and
colonization causes a persistent inflammatory response. H. pylori-induced gastritis is the …

Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Helicobacter pylori Infection

S Suerbaum, P Michetti - New England Journal of Medicine, 2002 - Mass Medical Soc
H. pylori is one of the most common bacterial infections in human beings, and its discovery
20 years ago altered the diagnosis and treatment of gastroduodenal disease. This review …

Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

[HTML][HTML] Helicobacter pylori persistence: biology and disease

MJ Blaser, JC Atherton - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …

Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation

J Berkes, VK Viswanathan, SD Savkovic, G Hecht - Gut, 2003 - gut.bmj.com
The effects of pathogenic organisms on host intestinal epithelial cells are vast. Innumerable
signalling pathways are triggered leading ultimately to drastic changes in physiological …

NF-κB signaling in gastric cancer

O Sokolova, M Naumann - Toxins, 2017 - mdpi.com
Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …

THE PATHOGENESIS OF HELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

JC Atherton - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Helicobacter infection and gastric neoplasia

RM Peek Jr, JE Crabtree - The Journal of Pathology: A Journal …, 2006 - Wiley Online Library
Chronic gastritis induced by Helicobacter pylori is the strongest known risk factor for
adenocarcinoma of the distal stomach, yet only a minority of people who harbour this …