Acquired chromosomal anomalies (most commonly translocations) in lymphoma and
leukemia usually result in either activation of a quiescent gene (by means of …

Hairy cell leukemia (HCL) is a distinct clinicopathological entity whose underlying genetic
lesion has remained a mystery for over half a century. The BRAF V600E mutation is now …

Background Hairy-cell leukemia (HCL) is a well-defined clinicopathological entity whose
underlying genetic lesion is still obscure. Methods We searched for HCL-associated …

The computational identification of oncogenic lesions is still a key open problem in cancer
biology. Although several methods have been proposed, they fail to model how such events …

Objective.—Diagnostic hematopathology depends on the applications of flow cytometric
immunophenotyping and immunohistochemical immunophenotyping combined with the …

Hairy cell leukemia (HCL) shows unique clinicopathological and biological features. HCL
responds well to purine analogs but relapses are frequent and novel therapies are required …

Context.—Beginning with the immunologic classifications of Lukes and Collins and Kiel and
culminating in the Revised European-American Lymphoma and World Health Organization …

Presence of the balanced translocation t (11; 14)(q13; q32) and the consequent
overexpression of cyclin D1 found in mantle cell lymphoma (MCL) has been shown to be of …

Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic
neoplasms, mantle cell lymphoma and Burkitt’s lymphoma - PMC Back to Top Skip to main …

Mantle cell lymphoma (MCL) diagnosis first relies on morphology and phenotype that may
overlap with other B-cell lymphomas. Therefore, the demonstration of t (11; 14)(q13; q32) …